Compare Bosutinib To Imatinib In Subjects With Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive CML



Status:Completed
Conditions:Other Indications, Blood Cancer
Therapuetic Areas:Oncology, Other
Healthy:No
Age Range:18 - Any
Updated:1/10/2019
Start Date:February 5, 2008
End Date:May 27, 2015

Use our guide to learn which trials are right for you!

A PHASE 3 RANDOMIZED, OPEN-LABEL STUDY OF BOSUTINIB VERSUS IMATINIB IN SUBJECTS WITH NEWLY DIAGNOSED CHRONIC PHASE PHILADELPHIA CHROMOSOME POSITIVE CHRONIC MYELOGENOUS LEUKEMIA

Two-arm, randomized, open-label trial designed to evaluate the efficacy and safety of
bosutinib alone compared to imatinib alone in subjects newly diagnosed with chronic phase
Chronic Myelogenous Leukemia (CML). The primary endpoint is cytogenetic response rate at one
year.


Inclusion Criteria:

- Cytogenetic diagnosis of chronic phase Ph+ CML diagnosed less than 6 months.

- Diagnosis of CML chronic phase confirmed.

- Adequate hepatic and renal function.

- Able to take oral tablets.

Exclusion Criteria:

- Exclusions include Philadelphia negative CML.

- Prior anti-leukemia treatment.

- Prior stem cell transplant.
We found this trial at
33
sites
1868
mi
from 98109
Indianapolis, IN
Click here to add this to my saved trials
5347 Main St # 203
New Port Richey, Florida 34652
2500
mi
from 98109
New Port Richey, FL
Click here to add this to my saved trials
24 Sturtevant St
Orlando, Florida 32806
2547
mi
from 98109
Orlando, FL
Click here to add this to my saved trials
Anaheim, California 92801
979
mi
from 98109
Anaheim, CA
Click here to add this to my saved trials
Atlanta, Georgia 30341
2176
mi
from 98109
Atlanta, GA
Click here to add this to my saved trials
6410 Rockledge Dr #660
Bethesda, Maryland 20817
(301) 571-0019
Center for Cancer & Blood Disorders Widely recognized for its compassionate, expert care, the Center...
2314
mi
from 98109
Bethesda, MD
Click here to add this to my saved trials
Beverly Hills, California 90211
?
mi
from 98109
Beverly Hills, CA
Click here to add this to my saved trials
Brownstown, Michigan 48183
?
mi
from 98109
Brownstown, MI
Click here to add this to my saved trials
Chattanooga, Tennessee 37404
2085
mi
from 98109
Chattanooga, TN
Click here to add this to my saved trials
Cherry Hill, New Jersey
2380
mi
from 98109
Cherry Hill, NJ
Click here to add this to my saved trials
Cherry Hill, New Jersey 08003
?
mi
from 98109
Cherry Hill, NJ
Click here to add this to my saved trials
Dearborn, Michigan 48126
1927
mi
from 98109
Dearborn, MI
Click here to add this to my saved trials
2799 W Grand Blvd
Detroit, Michigan 48202
(313) 916-2600
Henry Ford Hospital Founded in 1915 by auto pioneer Henry Ford and now one of...
1930
mi
from 98109
Detroit, MI
Click here to add this to my saved trials
Detroit, Michigan 48322
?
mi
from 98109
Detroit, MI
Click here to add this to my saved trials
Farmington, New Mexico 87401
1047
mi
from 98109
Farmington, NM
Click here to add this to my saved trials
Fountain Valley, California 92708
988
mi
from 98109
Fountain Valley, CA
Click here to add this to my saved trials
Hazard, Kentucky 41701
2094
mi
from 98109
Hazard, KY
Click here to add this to my saved trials
1515 Holcombe Blvd
Houston, Texas 77030
 713-792-2121
University of Texas M.D. Anderson Cancer Center The mission of The University of Texas MD...
1892
mi
from 98109
Houston, TX
Click here to add this to my saved trials
Hudson, Florida 34667
?
mi
from 98109
Hudson, FL
Click here to add this to my saved trials
1874
mi
from 98109
Indianapolis, IN
Click here to add this to my saved trials
La Jolla, California 92093
1049
mi
from 98109
La Jolla, CA
Click here to add this to my saved trials
La Jolla, California
1055
mi
from 98109
La Jolla, CA
Click here to add this to my saved trials
La Plata, Buenos Aires
6951
mi
from 98109
La Plata,
Click here to add this to my saved trials
New Port Richey, Florida 34652
2501
mi
from 98109
New Port Richey, FL
Click here to add this to my saved trials
Salinas, Kansas 67401
?
mi
from 98109
Salinas, KS
Click here to add this to my saved trials
San Diego, California 92103
1063
mi
from 98109
San Diego, CA
Click here to add this to my saved trials
230 Nebraska St.
Sioux City, Iowa 51101
712-252-0088
Siouxland Hematology-Oncology Associates, LLP Siouxland Hematology-Oncology Associates (SHOA) provides medical oncology treatment. In addition to...
1308
mi
from 98109
Sioux City, IA
Click here to add this to my saved trials
Somerville, New Jersey 08876
2378
mi
from 98109
Somerville, NJ
Click here to add this to my saved trials
300 Pasteur Drive
Stanford, California 94304
704
mi
from 98109
Stanford, CA
Click here to add this to my saved trials
Stanford, California 94305
705
mi
from 98109
Stanford, CA
Click here to add this to my saved trials
300 Pasteur Dr
Stanford, California 94305
(650) 723-4000
Stanford Univ Med Ctr The Medical Center is uniquely advantaged by its location on the...
704
mi
from 98109
Stanford, CA
Click here to add this to my saved trials
Tarpon Springs, Florida 34689
2504
mi
from 98109
Tarpon Springs, FL
Click here to add this to my saved trials
818 N. Emporia, #403
Wichita, Kansas 67214
(316) 262-4467
Cancer Center of Kansas The physicians of Cancer Center are hematologists and oncologists. The staff...
1435
mi
from 98109
Wichita, KS
Click here to add this to my saved trials