Prevalence of Lymphoma in IBD
Status: | Completed |
---|---|
Conditions: | Irritable Bowel Syndrome (IBS), Lymphoma, Gastrointestinal |
Therapuetic Areas: | Gastroenterology, Oncology |
Healthy: | No |
Age Range: | 18 - Any |
Updated: | 4/21/2016 |
Start Date: | April 2006 |
End Date: | October 2008 |
Prevalence and Risk Factor for Lymphoproliferative Disease in Patients With Inflammatory Bowel Disease
Patients with inflammatory bowel disease (IBD) may be at increased risk of lymphoma. The
majority of lymphomas in patients with IBD occur in areas of active inflammation. The
relationship between IBD and lymphoproliferative disease is however unclear, since both
chronic inflammation as well as medications used to treat IBD (especially immunosuppressives
- Azathioprine or 6-MP - and anti-TNF alpha agents) have been associated with increased risk
of lymphoma. We plan to study the association between IBD and lymphoma in a large, mixed,
community based and referral population from the IBD database at Indiana University.
majority of lymphomas in patients with IBD occur in areas of active inflammation. The
relationship between IBD and lymphoproliferative disease is however unclear, since both
chronic inflammation as well as medications used to treat IBD (especially immunosuppressives
- Azathioprine or 6-MP - and anti-TNF alpha agents) have been associated with increased risk
of lymphoma. We plan to study the association between IBD and lymphoma in a large, mixed,
community based and referral population from the IBD database at Indiana University.
Inclusion Criteria:
- Inflammatory Bowel disease
- Lymphoma
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Indiana University Medical Center Indiana University Health is Indiana
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