Value of Fecal Calprotectin
| Status: | Completed |
|---|---|
| Conditions: | Irritable Bowel Syndrome (IBS), Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | April 2006 |
| End Date: | December 2011 |
Correlation of Fecal Calprotectin Level With the Clinical, Endoscopic, Histologic and Radiologic Activity in Inflammatory Bowel diseaseThe Value of Fecal Calprotectin for the Diagnosis and Assessment of Inflammatory Bowel Disease
For the main goal - the accuracy of calprotectin for the diagnosis of IBD - calprotectin
levels will be compared between patients with and without a diagnosis of IBD and the
sensitivity, specificity and accuracy will be determined. For the secondary aim - the
correlation between calprotectin levels and disease activity - in patients with IBD selected
from this cohort, we will determine the association between calprotectin levels and clinical
IBD score, serological markers (WBC, Hgb, Platelets, ESR, CRP, Albumin), endoscopic (disease
score, pathological activity) and radiological features (bowel wall thickening, enhancement,
edema, mesenteric inflammation).
levels will be compared between patients with and without a diagnosis of IBD and the
sensitivity, specificity and accuracy will be determined. For the secondary aim - the
correlation between calprotectin levels and disease activity - in patients with IBD selected
from this cohort, we will determine the association between calprotectin levels and clinical
IBD score, serological markers (WBC, Hgb, Platelets, ESR, CRP, Albumin), endoscopic (disease
score, pathological activity) and radiological features (bowel wall thickening, enhancement,
edema, mesenteric inflammation).
Inclusion Criteria:
- Calprotectin assay at IU in last 12 months
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Indiana University INDIANA UNIVERSITY is a major multi-campus public research institution, grounded in the liberal...
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