Collection Of Tissue, Blood, and Other Specimens From Patients With Head and Neck Tumors To Study the Causes, Diagnosis, Prevention and Treatment of Cancers

This is a protocol to collect tissues, blood, and other specimens from patients with
malignant or nonmalignant diseases of the head and neck. Collected specimens will be used in
laboratory studies to investigate the growth, development, and transformation of normal and
abnormal cells in the future.

Inclusion Criteria:

- Patients with head and neck diseases are eligible if they have had tissue, serum,
urine, or other specimens removed or collected for diagnostic or therapeutic purposes.

- Patients will be entered onto this protocol without preference for any racial or
ethnic group.

- Patients may have received prior chemotherapy, radiation, surgical therapy,
immunotherapy, or differentiation therapy.

- The specimen collected must be large enough to allow conventional testing necessary
for patient care, with the portion of the specimen reserved for research laboratory
analysis excised from residual tissue that would otherwise have been discarded.

Exclusion Criteria:

- Patients not giving informed consent will be excluded.