Memory and Insulin in Early Alzheimer's Disease



Status:Completed
Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:60 - Any
Updated:4/21/2016
Start Date:October 2007
End Date:May 2012

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Intranasal Insulin and Memory in Early Alzheimer's Disease

To determine which parts of the brain are involved in insulin-related memory improvement in
early Alzheimer's disease and cognitively normal older adults.

Functional MRI study to characterize the neuroanatomic correlates of acute exogenous
insulin-related improvements in cognitive performance in early Alzheimer's disease and
cognitively normal older adults. The role of the apoE-e4 allele in modulating brain insulin
responses is also addressed.

Inclusion Criteria:

- Patients with Early Alzheimer's disease

Exclusion Criteria:

- Patients with Late Alzheimer's disease
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