Penile Injection Anxiety
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Erectile Dysfunction |
| Therapuetic Areas: | Nephrology / Urology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 11/10/2018 |
| Start Date: | February 2007 |
| End Date: | December 2019 |
The purpose of this study is to help us understand more about your experience with penile
injection therapy. Many men become anxious when thinking about penile injections. We would
like to understand more about this anxiety. You will be asked to fill out questionnaires
before you start penile injection training, at each training visit, and then at your four
month follow-up visit.
injection therapy. Many men become anxious when thinking about penile injections. We would
like to understand more about this anxiety. You will be asked to fill out questionnaires
before you start penile injection training, at each training visit, and then at your four
month follow-up visit.
The treatment of erectile dysfunction (ED) following radical pelvic surgery has become an
increasingly important issue. For many men, oral medications for ED will not be effective
immediately postoperatively. These medications enhance the effect of nitric oxide secreted
from the cavernous nerves, however these nerves are usually transiently injured
intraoperatively diminishing the amount of nitric oxide available. Consequently, oral
medications are usually ineffective for up to 18 to 24 months postoperatively while the
cavernous nerves are healing. As a result, penile injection therapy is the primary treatment
for ED for those men. This treatment delivers intracavernosal vasodilators at the base of the
penis with a 29 gauge needle. This direct application produces consistent results and has
been found to be effective for 94% of injection users. Despite common sense and clinical
experience that indicates men become very anxious about penile injection therapy, anxiety has
rarely been assessed in studies of penile injection therapy. We have observed that men who
are initially reluctant about penile injection therapy are more likely to try this treatment
when they hear that the injection anxiety dissipates quickly, after only a few injections. We
unfortunately only have clinical observation to support our claim describing the course of
injection anxiety. This study would provide empirical data to support this claim and this
data will be used in describing the treatment and encouraging men to try injection therapy.
increasingly important issue. For many men, oral medications for ED will not be effective
immediately postoperatively. These medications enhance the effect of nitric oxide secreted
from the cavernous nerves, however these nerves are usually transiently injured
intraoperatively diminishing the amount of nitric oxide available. Consequently, oral
medications are usually ineffective for up to 18 to 24 months postoperatively while the
cavernous nerves are healing. As a result, penile injection therapy is the primary treatment
for ED for those men. This treatment delivers intracavernosal vasodilators at the base of the
penis with a 29 gauge needle. This direct application produces consistent results and has
been found to be effective for 94% of injection users. Despite common sense and clinical
experience that indicates men become very anxious about penile injection therapy, anxiety has
rarely been assessed in studies of penile injection therapy. We have observed that men who
are initially reluctant about penile injection therapy are more likely to try this treatment
when they hear that the injection anxiety dissipates quickly, after only a few injections. We
unfortunately only have clinical observation to support our claim describing the course of
injection anxiety. This study would provide empirical data to support this claim and this
data will be used in describing the treatment and encouraging men to try injection therapy.
Inclusion Criteria:
- History of a radical pelvic surgery (cystectomy, prostatectomy, low anterior
resection)
- Participating in the injection therapy program
- Ability to provide informed consent
- Ability to converse, write and read English
Exclusion Criteria:
- History of or currently receiving radiation therapy,
- History of or currently receiving chemotherapy,
- History of or currently receiving hormone therapy.
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Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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