Cytokine Kinetics Test to Assess the Presence or Absence of Tolerance in Organ Transplant
| Status: | Terminated |
|---|---|
| Conditions: | Renal Impairment / Chronic Kidney Disease |
| Therapuetic Areas: | Nephrology / Urology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 4/21/2016 |
| Start Date: | September 2006 |
| End Date: | June 2008 |
Cytokine Kinetics Assay to Assess the Presence or Absence of Tolerance in Organ Transplant Recipients
The purpose of this pilot study is to determine if there is clinical correlation between the
CKT and transplant recipients who are known to be on minimal or no immunosuppression
(presumed tolerant) and those who are on conventional amounts of immunosuppression and have
either experienced rejection (presumed hyper-responsive to donor) or have not experienced
rejection (unknown responsive state).
CKT and transplant recipients who are known to be on minimal or no immunosuppression
(presumed tolerant) and those who are on conventional amounts of immunosuppression and have
either experienced rejection (presumed hyper-responsive to donor) or have not experienced
rejection (unknown responsive state).
Inclusion Criteria:
- Kidney or liver transplant recipients for whom donor cells are available
Exclusion Criteria:
- HcT <32%
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