Ramanspectroscopy in Barrett's Esophagus



Status:Completed
Conditions:Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - 85
Updated:4/21/2016
Start Date:October 2004
End Date:October 2007

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In-Vivo Raman Spectroscopy of Barrett's Esophagus

This study is being done to see if a new device, called near-infrared Raman spectroscopy,
can provide similar information as that obtained from taking biopsies of the lining of your
Barrett's esophagus

In the search for means to enhance the surveillance of BE, optical spectroscopy is emerging
as a candidate with high potential. Optical spectroscopic techniques measure specific
light-tissue interactions, such as fluorescence, elastic scattering, and Raman (inelastic)
scattering, which provide objective and quantitative diagnostic information about the
molecular and/or structural status of tissue. Moreover, optical spectroscopy has the
capacity to identify tissue pathology in situ in a rapid and non-destructive fashion. Among
the optical spectroscopic techniques, near-infrared Raman spectroscopy (NIRS) is
particularly promising because of the wealth of molecular-specific information contained in
its spectra

Inclusion Criteria:

- Closed to further enrollment
We found this trial at
1
site
Rochester, Minnesota 55905
?
mi
from
Rochester, MN
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