Germline BRCA1 and BRCA2 Mutations in Jewish Women Affected by Breast Cancer
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Breast Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 19 - Any |
| Updated: | 1/5/2019 |
| Start Date: | March 1997 |
| End Date: | December 2019 |
The purpose of this project is to further characterize inherited predisposition to breast
cancer mediated by specific BRCA alleles (BRACA1 185delAG and 5382insC; BRCA2 6174delT) among
Jewish women.
cancer mediated by specific BRCA alleles (BRACA1 185delAG and 5382insC; BRCA2 6174delT) among
Jewish women.
Inclusion Criteria:
- Patients are eligible for the study if they are over 18 years of age, identify their
ancestry as Jewish (both Sephardic and Ashkenazi Jews are eligible), have or have had
a diagnosis of breast cancer, and are able to give informed consent.
- Relatives, age 18 or older, of the patients who meet eligibility criteria above and
are found to have a specific BRCA1 or BRCA2 mutation if they are able to give informed
consent.
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Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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