Adrenal Scans With Radioiodine-Labeled Norcholesterol (NP-59)
| Status: | Completed |
|---|---|
| Conditions: | Women's Studies |
| Therapuetic Areas: | Reproductive |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 4/21/2016 |
| Start Date: | July 1977 |
| End Date: | March 2011 |
The purpose of this study is to find out if your adrenal glands are normal or abnormal. This
can be determined by whether or not your adrenal gland concentrates more of a labeled
building block of adrenal hormone, norcholesterol. This labeled material had been used as an
investigative diagnostic tool for imaging adrenal glands for many years with success in our
hands. This is a diagnostic procedure. CT, MRI and Ultrasound can determine the size and
presence or absence of tumor but cannot assess the function of the adrenal glands. To
determine hormone concentrations from blood samples would involve more invasive
catherization.
can be determined by whether or not your adrenal gland concentrates more of a labeled
building block of adrenal hormone, norcholesterol. This labeled material had been used as an
investigative diagnostic tool for imaging adrenal glands for many years with success in our
hands. This is a diagnostic procedure. CT, MRI and Ultrasound can determine the size and
presence or absence of tumor but cannot assess the function of the adrenal glands. To
determine hormone concentrations from blood samples would involve more invasive
catherization.
To investigate the feasibility of using NP-59 to localize adrenal tumors and assess their
functions under the influence of pharmacological manipulations.
functions under the influence of pharmacological manipulations.
Inclusion Criteria:
- Patient with clinical and laboratory suspicions of hypersecretion of adrenal cortical
hormones
Exclusion Criteria:
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