Genetic Susceptibility to Lung Cancer in Never Smokers
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Lung Cancer, Cancer, Other Indications |
| Therapuetic Areas: | Oncology, Other |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 6/7/2018 |
| Start Date: | June 2005 |
| End Date: | June 2019 |
The purpose of this study is to help us better understand the cellular changes that may lead
to the development of lung cancer. We want to compare people who have never smoked and yet
have been diagnosed with lung cancer to never smokers who have not developed lung cancer. We
hope to use the information obtained in this study as the basis for future studies and will
not regard the results from this study as final.
to the development of lung cancer. We want to compare people who have never smoked and yet
have been diagnosed with lung cancer to never smokers who have not developed lung cancer. We
hope to use the information obtained in this study as the basis for future studies and will
not regard the results from this study as final.
Inclusion Criteria:
- Cases will be eligible for inclusion if:
- They have been diagnosed with a lung cancer or have had previous surgical treatment
for their lung cancer and have smoked fewer than 100 cigarettes in their lifetime,
are/were not regular cigar or pipe smokers, and
- They have had no prior chemotherapy or radiation treatment within the last year
(Exception: genotyping analysis/screening can be performed on specimens from
individuals who had chemo/radiation treatment within the last year as germline DNA
will not be affected)
- They speak and read English
- They understand and agree to sign informed consent, and
- They agree to give us a blood sample, and
- They agree to complete the study questionnaire, and
- They agree to have their pathology information reviewed by study personnel.
- Controls will be eligible for inclusion if:
- They have not been diagnosed with any type of cancer, exclusive of nonmelanoma skin
cancer and have smoked fewer than 100 cigarettes in their lifetime, are/were not
regular cigar or pipe smokers, and
- They speak and read English
- They understand and agree to sign informed consent, and
- They agree to give us a blood sample, and
- They agree to complete the study questionnaire.
Exclusion Criteria:
- Subjects who do not meet the inclusion criteria for either the case or control groups
will not be eligible for this study.
- All individuals who otherwise meet the eligibility requirements above, but who have
had chemotherapy or radiation therapy within 1 year of evaluation will be excluded
(Exception: genotyping analysis/screening can be performed on specimens from
individuals who had chemo/radiation treatment within the last year as germline DNA
will not be affected).
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Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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