LSA4 Protocol for the Treatment of Advanced Pediatric and Adolescent Non-Hodgkins Lymphoma
| Status: | Completed |
|---|---|
| Conditions: | Lymphoma, Lymphoma |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | Any - 21 |
| Updated: | 4/21/2016 |
| Start Date: | May 1990 |
| End Date: | December 2008 |
Non-Hodgin's lymphoma is curable in 76% of patients. In nonlymphoblastic lymphmas, cancer
may return on average 3 months from beginning treatment and for lymphoblastic lymphomas, 6
months. To aggressively treat this cancer this study uses effective drugs in three parts:
- Induction ends on day 19
- Consolidation ends on day 38 or 42
- Maintenance may include up to 6 cycles
may return on average 3 months from beginning treatment and for lymphoblastic lymphomas, 6
months. To aggressively treat this cancer this study uses effective drugs in three parts:
- Induction ends on day 19
- Consolidation ends on day 38 or 42
- Maintenance may include up to 6 cycles
Inclusion Criteria:
- Non-Hodgkin's Lymphoma stages III, IV, IVA with
1. T cell lymphomas, any primary site irrespective of LDH level
2. large cell lymphomas, any primary site irrespective of LDH level
3. B cell lymphomas, any primary site with initial LDH of less than 500
Exclusion Criteria:
- B cell lymphomas, any primary site with initial LDH of less than 500 and initial CNS
or bone involvement
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Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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