Preliminary Study of Piclozotan in Patients With Motor Complications Associated With Parkinson's Disease
| Status: | Completed |
|---|---|
| Conditions: | Parkinsons Disease |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 40 - 85 |
| Updated: | 4/21/2016 |
| Start Date: | April 2007 |
| End Date: | July 2008 |
The purpose of this study is to obtain preliminary information on the effect of piclozotan
on motor complications associated with Parkinson's Disease.
on motor complications associated with Parkinson's Disease.
Main Inclusion Criteria:
- Idiopathic Parkinson's disease for at least 5 years
- Presence of motor fluctuations and dyskinesia
- Stable regimen of levodopa/carbidopa for 30 days
- At least 25% response/improvement in UPDRS part III scores after dosing with regular
PD medications
- MMSE score of 25 or higher
Main Exclusion Criteria:
- Atypical or secondary parkinsonism.
- Prior use of neuroleptic agents.
- History of intracranial procedures for PD.
- Active psychosis.
- History of drug or alcohol abuse in past 12 months.
- Cardiac conduction system abnormality.
- Predisposing medical condition that causes nausea or vomiting or routine use of an
anti-emetic.
We found this trial at
6
sites
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SUNY Downstate Medical Center Formally known as The State University of New York Health Science...
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