Axitinib (AG 013736) As Second Line Therapy For Metastatic Renal Cell Cancer



Status:Completed
Conditions:Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:1/11/2019
Start Date:September 3, 2008
End Date:February 25, 2016

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AXITINIB (AG-013736) AS SECOND LINE THERAPY FOR METASTATIC RENAL CELL CANCER: AXIS TRIAL

The study is designed to demonstrate that axitinib (AG-013736) is superior to sorafenib in
delaying tumor progression in patients with metastatic renal cell cancer after failure of one
first line regimen.


Inclusion Criteria:

- Histologically or cytologically confirmed renal cell cancer with a component of clear
cell subtype, with metastasis

- Evidence of measurable disease

- Must have failed one prior systemic first-line regimen for metastatic renal cell
cancer

Exclusion Criteria:

- Prior treatment for metastatic renal cell cancer with more that one systemic first
line therapy

- Major surgery less than 4 weeks or radiation less than 2 weeks of starting study drug
We found this trial at
147
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185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
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330 Brookline Ave
Boston, Massachusetts 02215
617-667-7000
Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
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3550 Jerome Avenue
Bronx, New York 10467
(718) 920-4321
Montefiore Medical Center As the academic medical center and University Hospital for Albert Einstein College...
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3840 Broadway
Fort Myers, Florida 33901
(239) 275-6400
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2220 Pierce Ave
Nashville, Tennessee 37232
615-936-8422
Vanderbilt-Ingram Cancer Center The Vanderbilt-Ingram Cancer Center, located in Nashville, Tenn., brings together the clinical...
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1211 Medical Center Dr
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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1400 South Orange Avenue
Orlando, Florida 32806
(407) 648-3800
M.D. Anderson Cancer Center at Orlando For more than twenty years, our cancer center has...
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1414 Kuhl Avenue
Orlando, Florida 32806
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825 Eastlake Ave E
Seattle, Washington 98109
(206) 288-7222
Seattle Cancer Care Alliance Seattle Cancer Care Alliance (SCCA) is a cancer treatment center that...
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131 Lila Doyle Drive
Seneca, South Carolina 29672
(864) 888-3717
Cancer Centers of the Carolinas - Seneca Cancer Centers of the Carolinas is now Cancer...
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1500 E Medical Center Dr
Ann Arbor, Michigan 48109
(734) 936-4000
University of Michigan Health System The University of Michigan is home to one of the...
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Arlington, Virginia 22205
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Aurora, Colorado 80012
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Aurora, Colorado 80045
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Austin, Texas 78705
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Austin, Texas 78705
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Austin, Texas 78731
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Austin, Texas 78758
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Boise, Idaho 83712
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Cape Coral, Florida 33914
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Carmel, Indiana 46032
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Cary, North Carolina 27511
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Cedar Park, Texas 78613
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171 Ashley Avenue
Charleston, South Carolina 29425
843-792-1414
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
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Chattanooga, Tennessee 37404
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Chesapeake, Virginia 23320
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10900 Euclid Ave
Cleveland, Ohio 44106
216-368-2000
Case Western Reserve Univ Continually ranked among America's best colleges, Case Western Reserve University has...
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2049 E 100th St
Cleveland, Ohio 44106
(216) 444-2200
Cleveland Clinic Foundation The Cleveland Clinic (formally known as The Cleveland Clinic Foundation) is a...
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Colorado Springs, Colorado 80907
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Columbia, Missouri 65201
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2650 Kenny Road
Columbus, Ohio 43221
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281 W. Lane Ave
Columbus, Ohio 43210
(614) 292-6446
Ohio State University The Ohio State University’s main Columbus campus is one of America’s largest...
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Deerfield Beach, Florida 33442
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Denver, Colorado 80218
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Denver, Colorado 80218
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Detroit, Michigan 48201
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Durham, North Carolina 27710
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2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111
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Easley, South Carolina 29640
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1144 North Road Street
Elizabeth City, North Carolina 27909
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Elizabeth City, North Carolina 27909
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Englewood, Florida 34223
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Eugene, Oregon 97401
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8503 Arlington Blvd., Ste. 400
Fairfax, Virginia 22031
(703) 280-5390
Virginia Cancer Specialists, PC Now the world's most advanced cancer treatment capabilities can be found...
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Farmington Hills, Michigan 48334
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Fishers, Indiana 46037
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Fort Worth, Texas 76177
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Fort Worth, Texas 76177
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Franklin, Tennessee 37067
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Fruitland, Idaho 83619
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Gainesville, Virginia 20155
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Greenfield, Indiana 46140
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Greenville, South Carolina 29605
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30 Prospect Ave
Hackensack, New Jersey 07601
(201) 996-2000
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Hampton, Virginia 23666
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Hermitage, Tennessee 37076
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500 University Dr
Hershey, Pennsylvania 17033
(717) 531-6955
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Houston, Texas 77030
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1515 Holcombe Blvd
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Indianapolis, Indiana 46227
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9280 W. Sunset Road Suite 100
Las Vegas, Nevada 89148
702.952.1251
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Lebanon, Tennessee 37087
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Los Angeles, California 90095
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