Optical Coherence Tomography of the Airway for Lung Cancer or Lung Disease
| Status: | Withdrawn |
|---|---|
| Conditions: | Lung Cancer, Lung Cancer, Cancer, Cancer, Cancer, Cancer, Cancer, Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 4/21/2016 |
| Start Date: | April 2008 |
| End Date: | February 2011 |
Optical Coherence Tomography of Human Airways
RATIONALE: Diagnostic procedures, such as optical coherence tomography, may help find and
diagnose lung cancer or precancerous cells.
PURPOSE: This phase I trial is studying how well optical coherence tomography of the airway
works in detecting abnormal cells in patients undergoing surgery for lung cancer or lung
disease.
diagnose lung cancer or precancerous cells.
PURPOSE: This phase I trial is studying how well optical coherence tomography of the airway
works in detecting abnormal cells in patients undergoing surgery for lung cancer or lung
disease.
OBJECTIVES:
- Correlate optical coherence tomography images of the airway with airway histology.
- Develop an imaging technique to detect premalignant airway epithelial changes
(carcinoma in situ, dysplasia) to study the transformation process as well as intervene
and prevent the development of lung cancer.
OUTLINE: Bronchoscopic imaging and optical coherence tomography are performed on lung tissue
samples collected during surgery. All imaged areas are marked. The marked areas are then
excised and fixed in formalin for histopathologic analysis.
- Correlate optical coherence tomography images of the airway with airway histology.
- Develop an imaging technique to detect premalignant airway epithelial changes
(carcinoma in situ, dysplasia) to study the transformation process as well as intervene
and prevent the development of lung cancer.
OUTLINE: Bronchoscopic imaging and optical coherence tomography are performed on lung tissue
samples collected during surgery. All imaged areas are marked. The marked areas are then
excised and fixed in formalin for histopathologic analysis.
DISEASE CHARACTERISTICS:
- Undergoing pneumonectomy or lobectomy for malignant or benign lung processes
PATIENT CHARACTERISTICS:
- Not specified
PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
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Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center We all know...
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