A Retrospective Analysis of Patients With Full Thickness Wounds in Limbs With Critical Ischemia



Status:Completed
Conditions:Peripheral Vascular Disease, Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:April 2007
End Date:April 2008

Use our guide to learn which trials are right for you!

Once the patients are identified that have a full thickness wound on a limb clearly
identified as having critical limb ischemia, these patients will be evaluated. The data that
will be extracted from each chart will include patient's age, patient's gender, number of
office visits, presence of diabetes, presence of osteomyelitis, type and amount of
antibiotic administered, number of hyperbaric oxygen treatments, and if the wound healed.

Clinicians have even learned to group patients into different etiologic categories based on
underlying disease such as diabetes mellitus, decubitus ulcer, surgical site infection,
venous insufficiency, arterial insufficiency and others. It seems that wounds have been
grouped into these categories because of their common barriers, which should allow us more
precise algorithms and may provide better outcomes. That is diabetics tend to have the
barriers of poor perfusion, endothelial cell dysfunction, white blood cell dysfunction,
hyperglycemia, neuropathy and repetitive trauma. Venous insufficiency patients tend to have
perivascular cuffing and peri wound edema. However patients with venous leg ulcers commonly
have peripheral arterial disease and diabetes (3). The point is regardless of the etiology
of the wound every patient must be evaluated for all barriers on every visit. Arbitrarily
dividing chronic wounds in the etiologic categories has not significantly improved wound
healing outcomes.

Inclusion Criteria:

- The inclusion criteria for the study are patients that demonstrate the following:

- A limb with a TCpO2 less than 20 with a full thickness wound.

- Initial visit from August 1, 2002 to December 31, 2005.

Exclusion Criteria:

- The exclusion criteria for the study are patients that demonstrate the following:

- Partial thickness wound or no wound in limb with critical ischemia.

- A medical record that does not clearly demonstrate critical limb ischemia or
does not clearly demonstrates a full thickness wound.
We found this trial at
1
site
?
mi
from
Lubbock, TX
Click here to add this to my saved trials