Comparison of Straumann BoneCeramic vs. Allograft Bone in Extraction Sockets

Subjects will undergo a single tooth extraction and then will be randomized to receive SBC
or FDBA. Following a healing period of 6 months, a core biopsy will be taken of the
augmented site and a dental implant will be placed. The subject will be followed for one
year following dental implant placement for implant success and survival.

Inclusion Criteria:

- Subjects must have voluntarily signed the informed consent form

- Subjects must be between the ages of 18 and 80

- Subjects must need a single tooth extraction in ADA sites 3-6 and 11-14 without
septal bone in the maxilla and in ADA sites 19-30 without septal bone in the mandible
and would benefit from prosthetic reconstruction with a dental implant

- Subjects must be committed to the study and the required follow-up visits

- Subjects must be in good general health as assessed by the Investigator

Exclusion Criteria:

- Presence of conditions requiring chronic routine prophylactic use of antibiotics

- Pregnancy

- Medical conditions requiring prolonged use of steroids

- History of leukocyte dysfunction and deficiencies

- History of bleeding disorders

- History of neoplastic disease requiring the use of chemotherapy

- History of radiation therapy to the head and neck

- Subjects with a history of renal failure

- Subjects with severe or uncontrolled metabolic bone disorders

- Uncontrolled endocrine disorders

- Subjects who knowingly have HIV or hepatitis

- Physical handicaps that would interfere with the ability to perform adequate oral
hygiene

- Subjects who have undergone administration of any investigational drug or device
within 30 days of enrollment in the study

- Alcoholism or drug abuse

- Subjects who are heavy smokers (>10 cigarettes per day or cigar equivalents) or chew
tobacco

- Conditions or circumstances, in the opinion of the Investigator, which would prevent
completion of study participation or interfere with analysis of study results, such
as history of non-compliance or unreliability

- Local inflammation including untreated periodontitis

- Mucosal diseases such as erosive lichen planus

- History of local radiation therapy

- Presence of oral lesions (such as ulcerations or malignancy)

- Bone defects that exclude implant restoration

- Subjects who have a full mouth plaque level >30% at the baseline visit

- Severe bruxing or clenching habits

- Persistent intra-oral infection

- Subjects presenting with an acute abscess in the tooth to be extracted or in the
adjacent teeth to the extraction site (sites with presence of asymptomatic chronic
lesions are eligible)

- Subjects with inadequate oral hygiene or unmotivated for adequate home care

- At the time of tooth extraction, if any bony wall is severely damaged or completely
lost (i.e., anything other than a four wall extraction socket)