Safety Study to Lower the Risk of Heart Failure is Also Effective in Reducing Stiffness of the Arteries
| Status: | Completed |
|---|---|
| Conditions: | High Blood Pressure (Hypertension) |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 50 - 85 |
| Updated: | 4/21/2016 |
| Start Date: | January 2009 |
| End Date: | April 2013 |
The Effects of Nebivolol on Aortic Impedance Parameters in Type 2 Diabetics
The study is being done to see if a drug shown to lower the risk of heart failure is also
effective in reducing the stiffness of the arteries.
effective in reducing the stiffness of the arteries.
To determine the effect of nebivolol versus metoprolol in Type 2 hypertensive diabetic
patients on systolic blood pressure and diastolic blood pressure.
patients on systolic blood pressure and diastolic blood pressure.
Inclusion Criteria:
- Established Type 2 diabetic not treated with insulin
- Stage 1 hypertensives blood pressure > 130/80 mmHg and < 160/100 mmHg
- BMI < 35
- Hemoglobin A1C < 8.5
- Must be postmenopausal or taking some form of birth control of surgically sterile
Exclusion Criteria:
- Acute myocardial infarction, unstable angina, stroke or TIA within the past year.
- Active angina in the last three months
- Diabetes requiring treatment with insulin
- Severe asthma
- Female who are pregnant, planning to be pregnant during the study period, lactating
or women of childbearing potential who are not using a medically approved method of
contraception
- Recent history of substance or alcohol abuse .
- Uncontrolled hypertension systolic blood pressure >160mmHg or diastolic blood
pressure > 100 mmHg
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