Correlation of Cerebral State Index With the Richmond Agitation-Sedation Scale in Mechanically Ventilated ICU Patients
| Status: | Terminated |
|---|---|
| Conditions: | Hospital |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 18 - 85 |
| Updated: | 4/21/2016 |
| Start Date: | May 2008 |
| End Date: | February 2010 |
Correlation of the Cerebral State Index With the Richmond Agitation-Sedation Scale in ICU Patients Who Are Sedated and Mechanically Ventilated: A Pilot Study
The purpose of this study is to correlate the cerebral state index obtained from a cerebral
state monitor with the Richmond Agitation-Sedation Scale assessment performed on sedated and
mechanically ventilated intensive care patients.
state monitor with the Richmond Agitation-Sedation Scale assessment performed on sedated and
mechanically ventilated intensive care patients.
Currently there are no objective methods to measure levels of sedation in all ICU patient
populations. This generally does not become problematic in most patients. However, certain
populations cannot be assessed by standard means. These populations would include patients
who are quadriplegic and those who are being treated with neuromuscular blocking agents. The
current norm is to use a sedation scale such as the Richmond Agitation-Sedation Scale to
assess the patient's level of sedation. An alternative to this would be to use an EEG based
method that monitors brain activity. New methods of monitoring brain activity, using
cerebral state monitors may provide an effective means of monitoring sedation. The cerebral
state monitor, however, and the parameters it provides, the cerebral state index, has not
been tested in an ICU setting. Correlating the measurements gained from the cerebral state
monitor with the RASS assessment from sedated ICU patients may allow us to develop a method
of monitoring sedation in populations that were impossible to monitor previously. Accurately
monitoring the level of sedation in these patients may help decrease the incidence of
over-sedation and under-sedation.
populations. This generally does not become problematic in most patients. However, certain
populations cannot be assessed by standard means. These populations would include patients
who are quadriplegic and those who are being treated with neuromuscular blocking agents. The
current norm is to use a sedation scale such as the Richmond Agitation-Sedation Scale to
assess the patient's level of sedation. An alternative to this would be to use an EEG based
method that monitors brain activity. New methods of monitoring brain activity, using
cerebral state monitors may provide an effective means of monitoring sedation. The cerebral
state monitor, however, and the parameters it provides, the cerebral state index, has not
been tested in an ICU setting. Correlating the measurements gained from the cerebral state
monitor with the RASS assessment from sedated ICU patients may allow us to develop a method
of monitoring sedation in populations that were impossible to monitor previously. Accurately
monitoring the level of sedation in these patients may help decrease the incidence of
over-sedation and under-sedation.
Inclusion Criteria:
- Admission the surgical-trauma intensive care unit at the Charleston Area Medical
Center General Hospital
- Adult (18-85 years of age)
- Anticipated duration of mechanical ventilation of at least 72 hours
Exclusion Criteria:
- Patients admitted with paralysis or a brain injury
- Patients who are deaf, blind, or have pre-existing dementia/delirium
We found this trial at
2
sites
Click here to add this to my saved trials
Click here to add this to my saved trials