Pilot Study Evaluating Stress Response and Immune Function in Mechanically Ventilated Patients With Alcohol Use Disorders Treated With Propofol or Midazolam
| Status: | Withdrawn |
|---|---|
| Conditions: | Psychiatric, Pulmonary |
| Therapuetic Areas: | Psychiatry / Psychology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | March 2009 |
| End Date: | March 2009 |
Randomized Clinical Trial Comparing Propofol and Midazolam in Mechanically Ventilated Critically Ill Patients With Alcohol Use Disorders: An Open Label Pilot Study
The aim of this study is to evaluate the effects of the sedatives propofol and midazolam on
stress response and immune function in critically ill patients with alcohol use disorders
who are undergoing mechanical ventilation.
stress response and immune function in critically ill patients with alcohol use disorders
who are undergoing mechanical ventilation.
No detailed description
Inclusion Criteria:
- Diagnosis of alcohol use disorders
- Need for invasive mechanical ventilation
- Need for continuous intravenous infusion of sedative(s)
Exclusion Criteria:
- Age < 18 years
- Pregnant women
- Prisoners
- Receiving propofol prior to randomization
- Patient experiencing active alcohol withdrawal
- Immunosuppression
- Shock
- Attending physician does not feel patient is candidate to receive either propofol or
midazolam
- Patient has contraindication(s) to receiving either propofol or midazolam
- Inability to enroll patient within 96 hours after initiation of mechanical
ventilation
- Transfer from another intensive care unit
We found this trial at
2
sites
Virginia Commonwealth University Medical Center The Virginia Commonwealth University Health System is an urban, comprehensive...
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Richmond, Virginia 23298
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