Burn Micronutrient Repletion Pilot Study

Burn injury patients undergo a series of metabolic events that, if untreated, could lead to
severe physical impairment and even death. Antioxidants minimize free radical damage by
neutralizing the chemical reaction as well as promoting cellular repair. Currently there is
no consistent protocol for micronutrient repletion in adult burn patients. The aim of this
study is to evaluate the effectiveness of the current vitamin regimen in comparison to the
novel vitamin and mineral supplementation protocol developed by the research team. Dosages
for oral and intravenous supplementation are based on current literature. The combination of
intravenous and enteral treatment is important due to gastrointestinal mucosal swelling
related to post-burn fluid resuscitation. Measurable health outcomes will include rate of
infection, length of hospital stay, mortality rate, hospital cost, number of days in
intensive care unit, number of ventilator-dependent days and wound healing. The
investigators hypothesize that use of the novel vitamin and mineral supplement regimen will
improve adult burn patient outcomes.

Inclusion Criteria:

- patients who present at the burn unit with TBSA > 1%

Exclusion Criteria:

- less than 19 years old

- chronic renal failure

- chronic liver failure

- pregnancy or lactation

- patients who require parenteral nutrition