Diagnosis and Treatment of Sleep Apnea in Cerebrovascular Disease



Status:Completed
Conditions:High Blood Pressure (Hypertension), Insomnia Sleep Studies, Neurology, Neurology, Pulmonary, Pulmonary
Therapuetic Areas:Cardiology / Vascular Diseases, Neurology, Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:40 - Any
Updated:4/21/2016
Start Date:December 2008
End Date:September 2011

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Trial Summary
Trial Overview
Inclusion Criteria
Sleep apnea is common among Veterans with cerebrovascular disease (stroke or transient
ischemic attack [TIA]), leads to hypertension, and is associated with recurrent stroke and
death. Although continuous positive airway pressure (CPAP) safely treats sleep apnea, few
Veterans with cerebrovascular disease are diagnosed with sleep apnea or offered treatment.

The project sought to evaluate whether a diagnostic and therapeutic intervention strategy
among Veterans with cerebrovascular disease and hypertension using unattended
polysomnography and auto-titrating CPAP with a targeted adherence evaluation and educational
protocol resulted in: an improved rate of diagnosed sleep apnea, an improved rate of treated
sleep apnea, and improved blood pressure control.

Inclusion Criteria:

Stroke or Transient Ischemic Attack Hypertension

Exclusion Criteria:

- Prior diagnosis of sleep apnea or other sleep disorder

- Life expectancy < 6 months or Hospice

- Non-English speaker

- Unable/unwilling to use mask

- Inability to give informed consent

- Oxygen dependent COPD

- Chronic renal failure with dialysis

- Active Suicidal Ideation
We found this trial at
2
sites
Richard L. Roudebush VA Medical Center
Indianapolis, Indiana 46202
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Indianapolis, IN
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VA Connecticut Health Care System
West Haven, Connecticut 06516
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West Haven, CT
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