PROPHESYS 3: Observational Study on Predictors of Response in Patients With Treatment-naïve Chronic Hepatitis C Initiated on Treatment With Pegasys (Peginterferon Alfa-2a) or Peginterferon-alfa-2b



Status:Completed
Conditions:Hepatitis, Hepatitis, Hepatitis
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:January 2008
End Date:June 2011

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Prospective Observational Study on Predictors of Early On-treatment Response and Sustained Virological Response in a Cohort of Treatment naïve HCV-infected Patients Treated With Pegylated Interferons

This observational study will assess predictors of early on-treatment and sustained
virological response in treatment-naïve patients with chronic hepatitis C initiated on
treatment with Pegasys (peginterferon alfa-2a) or peginterferon alfa-2b and ribavirin. Data
will be collected during the treatment period (24 or 48 weeks) and 12 and 24 weeks after the
end of treatment. Target sample size is <2000.


Inclusion Criteria:

- adult patients, >/= 18 years of age

- chronic hepatitis C

- HIV HCV co-infection allowed

- informed consent to data collection

Exclusion Criteria:

- co-infection with HBV

- previous treatment with peginterferon and/or ribavirin
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90
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Fayetteville, North Carolina 28304
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Albuquerque, NM
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Birmingham, AL
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Boston, MA
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Camp Hill, PA
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Catskill, NY
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Chapel Hill, NC
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Charlotte, North Carolina 28207
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Charlotte, NC
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Charlottesville, VA
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Chattanooga, TN
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Chicago, IL
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Cincinnati, OH
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Cleveland, OH
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Dallas, TX
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Detroit, MI
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Dothan, AL
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DuBois, PA
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Egg Harbour Township, New Jersey 08234
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Fairfax, VA
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Flushing, NY
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Grand Rapids, MI
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Hackensack, NJ
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Hartford, CT
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Honolulu, HI
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Houston, TX
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Huntington, West Virginia 25701
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Iowa City, IA
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Jackson, MS
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Kansas City, KS
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La Jolla, CA
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Lebanon, NH
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Lexington, KY
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Springfield, Massachusetts 01199
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St Louis, MO
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1700 Southwest College Avenue
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Voorhees, NJ
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West Nashville, Tennessee 37205
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West Nashville, TN
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Worcester, MA
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