Vitamin D Levels in Stage IV Colorectal Cancer Patients
| Status: | Completed |
|---|---|
| Conditions: | Colorectal Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | February 2010 |
| End Date: | October 2014 |
Vitamin D Levels in Stage IV Colorectal Cancer Patients: A Phase II Study
The purpose of this study is to find out what effects, good and/or bad, vitamin D blood
levels has on stage IV colorectal cancer. Tbe doctors want to see if it is possible to
increase low vitamin D levels into normal range using vitamin D supplements taken by mouth.
Low vitamin D levels have been associated with worse outcomes in persons who have cancer.
Low vitamin D may also cause people to have symptoms such as pain and fatigue. We want to
see if increasing low vitamin D levels will help improve cancer outcomes. Vitamin D is
routinely repleted in all subjects known to be vitamin D deficient. Therefore, the treatment
given would be considered standard of care.
levels has on stage IV colorectal cancer. Tbe doctors want to see if it is possible to
increase low vitamin D levels into normal range using vitamin D supplements taken by mouth.
Low vitamin D levels have been associated with worse outcomes in persons who have cancer.
Low vitamin D may also cause people to have symptoms such as pain and fatigue. We want to
see if increasing low vitamin D levels will help improve cancer outcomes. Vitamin D is
routinely repleted in all subjects known to be vitamin D deficient. Therefore, the treatment
given would be considered standard of care.
Inclusion Criteria:
- Patients with Stage IV (metastatic) colorectal cancer
- Baseline 25-hydroxy vitamin D level < 30 ng/ml
- Age ≥18 years of age
Exclusion Criteria:
- Current or previous malignancy except adequately treated non-melanoma skin cancer,
curatively treated in-situ cancer of the cervix, or other solid tumors curatively
treated with no evidence of disease for > 3 years
- Albumin < 3.2
- Patients on concurrent chronic steroids, other than those allowed for routine
antiemetics, or inhaled steroids
- Patients receiving phenobarbital, phenytoin, orlistat and cholestyramine
- Hypercalcemia (Calcium >10.5 mg/dl)
- Calcium x Phosphorus > 70 mg2/dL2
We found this trial at
5
sites
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
Click here to add this to my saved trials
1000 N Village Ave
Rockville Centre, New York 11570
Rockville Centre, New York 11570
(516) 256-3600
Memorial Sloan-Kettering at Mercy Medical Center Memorial Sloan Kettering Cancer Center Rockville Centre provides state-of-the-art...
Click here to add this to my saved trials