Safety Study of BMS-823778 in Subjects With Hypercholesterolemia
| Status: | Completed |
|---|---|
| Conditions: | High Cholesterol, High Cholesterol |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - 75 |
| Updated: | 4/21/2016 |
| Start Date: | June 2010 |
| End Date: | December 2010 |
A Double-Blind, Placebo-Controlled, Parallel-Group, Randomized, Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Effects of BMS-823778 in Non-Diabetic Subjects With Primary Hypercholesterolemia on a Stable Dose of Statin Therapy With or Without Ezetimibe
The purpose of this study is to assess the safety, tolerability and pharmacodynamic effects
on LDL cholesterol (LDL-C)
on LDL cholesterol (LDL-C)
Inclusion Criteria:
- Hypercholesterolemia
- Currently taking a stable daily dose of statin therapy
- Serum triglyceride level < 500mg/dl
Exclusion Criteria:
- History of myocardial infarction, coronary angioplasty or bypass grafts, valvular
disease or repair, unstable angina pectoris, transient ischemic attack, or
cerebrovascular accidents within six months prior to entry into the study
- Congestive heart failure
- Diabetes mellitus
- Active liver disease
- Impaired renal function
- Hepatitis C, B and HIV
This list is not inclusive; additional information is provided in the protocol
We found this trial at
7
sites
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