Evaluation of Donated Human Embryos Following in Vitro Fertilization
| Status: | Enrolling by invitation |
|---|---|
| Healthy: | No |
| Age Range: | 18 - 65 |
| Updated: | 4/6/2019 |
| Start Date: | July 2005 |
| End Date: | December 2025 |
Evaluation of Donated Human Embryos for Study of Normal and Abnormal Differentiation and Development Following in Vitro Fertilization.
Couples who have created excess embryos while undergoing IVF procedures, and who do not wish
to transfer those embryos or donate them to another couple may donate the extra embryos to
research. The embryos are then used to develop improved laboratory techniques and conditions
as well as testing the proficiency of laboratory staff.
to transfer those embryos or donate them to another couple may donate the extra embryos to
research. The embryos are then used to develop improved laboratory techniques and conditions
as well as testing the proficiency of laboratory staff.
Undergoing IVF treatment often results in the production of more embryos than can safely be
transferred at one time. These extra embryos are often cryopreserved for future use. In the
event that a couple decides that they do not want to proceed with using cryopreserved
embryos, these embryos can be discarded, donated to another couple, or donated to research.
Embryos that are donated to research are used to identify a group of parameters that have
significant predictive value for assisted reproductive technology outcomes. We hope to
develop future laboratory techniques as we gain a better knowledge of gamete development,
fertilization and implantation. We will test, standardize and implement better methods for
freezing embryos prior to employing these techniques in a clinical setting. We hope to
develop new methods to optimize the determination of genes and chromosomes in embryos. We
will test the proficiency of laboratory staff on techniques and/or procedures done in the IVF
laboratory. This study WILL NOT:create embryos for research, transfer embryos to an
individual, develop cell lines or clones.
transferred at one time. These extra embryos are often cryopreserved for future use. In the
event that a couple decides that they do not want to proceed with using cryopreserved
embryos, these embryos can be discarded, donated to another couple, or donated to research.
Embryos that are donated to research are used to identify a group of parameters that have
significant predictive value for assisted reproductive technology outcomes. We hope to
develop future laboratory techniques as we gain a better knowledge of gamete development,
fertilization and implantation. We will test, standardize and implement better methods for
freezing embryos prior to employing these techniques in a clinical setting. We hope to
develop new methods to optimize the determination of genes and chromosomes in embryos. We
will test the proficiency of laboratory staff on techniques and/or procedures done in the IVF
laboratory. This study WILL NOT:create embryos for research, transfer embryos to an
individual, develop cell lines or clones.
Inclusion Criteria:
Exclusion Criteria:
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