Ability of Near Infrared Spectroscopy to Isolate Compartments of the Extremity



Status:Completed
Conditions:Cardiology, Pain
Therapuetic Areas:Cardiology / Vascular Diseases, Musculoskeletal
Healthy:No
Age Range:18 - 75
Updated:8/17/2018
Start Date:January 2010
End Date:December 2016

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Near infrared spectroscopy (NIRS) provides a non-invasive means of continuously monitoring
tissue oxygenation, which may be useful for diagnosis of acute compartment syndrome (ACS).
Placement of these sensor pads on the surface of the skin must be such that light penetrates
the intended compartment without inadvertently obtaining measurements of an adjacent
compartment. The objective of this study is to examine whether the NIRS measurements of each
compartment truly represent the tissue perfusion of the intended compartment, as indicated by
the predictable decrease in muscle oxygenation of a given compartment in response to muscle
fatigue. The investigators hypothesize that the tissue oxygenation values of the stimulated
compartment will significantly decrease following muscle stimulation, indicating that the
intended muscle compartment was successfully isolated. Additionally, the investigators
hypothesize that NIRS values of unstimulated muscle compartments will not change from
baseline.


Inclusion Criteria:

- 18-75 years old

- no current extremity injuries

- willing to provide written informed consent

Exclusion Criteria:

- history of any anatomy-altering surgery to the extremity in question

- history of peripheral vascular disease

- history of pulmonary disease
We found this trial at
1
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Athens, Georgia 30606
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Athens, GA
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