Determinants of Medical and Surgical Treatment Outcomes in Chronic Sinusitis
| Status: | Completed |
|---|---|
| Conditions: | Sinusitis |
| Therapuetic Areas: | Otolaryngology |
| Healthy: | No |
| Age Range: | 18 - 90 |
| Updated: | 4/21/2016 |
| Start Date: | April 2011 |
| End Date: | March 2016 |
This research study will be completed by enrolling a prospective, observational cohort study
to evaluate medical versus surgical treatment outcomes for chronic sinus disease. This
investigation will compare quality of life outcomes between each treatment type, as well as
measure cellular and molecular markers of inflammation in the sinus mucosa, to create models
that predict improvement in quality of life following treatment.
to evaluate medical versus surgical treatment outcomes for chronic sinus disease. This
investigation will compare quality of life outcomes between each treatment type, as well as
measure cellular and molecular markers of inflammation in the sinus mucosa, to create models
that predict improvement in quality of life following treatment.
Inclusion Criteria:
- Adult (>= 18 years)
- Chronic rhinosinusitis as defined by the 2007 multi-disciplinary adult sinusitis
guidelines
- Able to complete all surveys/questionnaires in English
- Persistent symptoms following initial medical management
- Received at least 1 course of broad spectrum antibiotics or culture directed
antibiotics for at least a total of 14 days
- Received at least a 3 week trial of topical steroid sprays OR at least a 5 day trial
of systemic corticosteroid therapy.
- Counseled for subsequent treatment options including either medical management or
endoscopic sinus surgery
Exclusion Criteria:
- Children (<18 years)
- Unable to complete all surveys/questionnaires at baseline
We found this trial at
1
site
3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
Portland, Oregon 97239
503 494-8311
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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