12 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Patients With Type 2 Diabetes Mellitus



Status:Completed
Conditions:High Blood Pressure (Hypertension), Diabetes, Diabetes
Therapuetic Areas:Cardiology / Vascular Diseases, Endocrinology
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:June 2011
End Date:July 2012

Use our guide to learn which trials are right for you!

A Phase III Randomised, Double-blind, Placebo-controlled, Parallel Group, Efficacy and Safety Study of BI 10773 (10 mg, 25 mg) Administered Orally, Once Daily Over 12 Weeks in Hypertensive Patients With Type 2 Diabetes Mellitus

This trial will evaluate safety and efficacy of BI 10773 in hypertensive patients with type
2 diabetes. Since hyperglycaemia and hypertension are key risk factors for both micro- and
macrovascular complications, assessment of both glucose and blood pressure lowering effects
of BI 10773 in hypertensive patients with type 2 diabetes could provide clinically highly
relevant, new information for the use of BI 10773


Inclusion criteria:

1. Patients >=18 years with type 2 diabetes

2. HbA1c of >= 7.0% (53 mmol/mol) and =< 10% (86 mmol/mol)

3. Mean seated systolic blood pressure 130-159 mmHg and diastolic blood pressure 80-99
mmHg

Exclusion criteria:

1. Uncontrolled hyperglycaemia with a glucose level >240 mg/dl (>13.3 mmol/L) after an
overnight fast before randomization

2. Known or suspected secondary hypertension

3. Acute coronary syndrome (non-STEMI, STEMI and unstable angina pectoris), stroke or
transient ischemic attack within 3 months prior to informed consent
We found this trial at
33
sites
1714
mi
from 98109
Addison, IL
Click here to add this to my saved trials
2041
mi
from 98109
Akron, OH
Click here to add this to my saved trials
1184
mi
from 98109
Albuquerque, NM
Click here to add this to my saved trials
1708
mi
from 98109
Arlington Heights, IL
Click here to add this to my saved trials
Charlotte, North Carolina
2281
mi
from 98109
Charlotte, NC
Click here to add this to my saved trials
1733
mi
from 98109
Chicago, IL
Click here to add this to my saved trials
1681
mi
from 98109
Dallas, TX
Click here to add this to my saved trials
2715
mi
from 98109
Davie, FL
Click here to add this to my saved trials
2547
mi
from 98109
Edgewater, FL
Click here to add this to my saved trials
2076
mi
from 98109
Erie, PA
Click here to add this to my saved trials
1890
mi
from 98109
Houston, TX
Click here to add this to my saved trials
2038
mi
from 98109
Huntsville, AL
Click here to add this to my saved trials
2452
mi
from 98109
Jacksonville, FL
Click here to add this to my saved trials
1963
mi
from 98109
Kettering, OH
Click here to add this to my saved trials
2110
mi
from 98109
Knoxville, TN
Click here to add this to my saved trials
606
mi
from 98109
Lincoln, CA
Click here to add this to my saved trials
982
mi
from 98109
Long Beach, CA
Click here to add this to my saved trials
962
mi
from 98109
Los Angeles, CA
Click here to add this to my saved trials
2163
mi
from 98109
Marietta, GA
Click here to add this to my saved trials
1864
mi
from 98109
Memphis, TN
Click here to add this to my saved trials
2732
mi
from 98109
Miami, FL
Click here to add this to my saved trials
731
mi
from 98109
Orem, UT
Click here to add this to my saved trials
2508
mi
from 98109
Palm Harbor, FL
Click here to add this to my saved trials
2200
mi
from 98109
Pensacola, FL
Click here to add this to my saved trials
1116
mi
from 98109
Phoenix, AZ
Click here to add this to my saved trials
2521
mi
from 98109
Pinellas Park, FL
Click here to add this to my saved trials
2132
mi
from 98109
Pittsburgh, PA
Click here to add this to my saved trials
15
mi
from 98109
Port Orchard, WA
Click here to add this to my saved trials
1787
mi
from 98109
San Antonio, TX
Click here to add this to my saved trials
988
mi
from 98109
Tustin, CA
Click here to add this to my saved trials
947
mi
from 98109
West Hills, CA
Click here to add this to my saved trials
1435
mi
from 98109
Wichita, KS
Click here to add this to my saved trials
1152
mi
from 98109
Winnipeg,
Click here to add this to my saved trials