Idiopathic Diseases of Man
| Status: | Enrolling by invitation |
|---|---|
| Healthy: | No |
| Age Range: | Any |
| Updated: | 4/6/2019 |
| Start Date: | September 2011 |
| End Date: | December 2020 |
Idiopathic Diseases of Man (IDIOM)
This research is being done to learn more about possible genetic causes of currently
undiagnosed conditions, and to find out how the development of new technologies, such as DNA
sequencing, can increase knowledge of the role genetic variants play in disorders and
possibly how genetic variants may help de-termine the best treatment options.
The recent development of new technologies has increased our ability to understand how
genetic mutations are associated with disease. Using these technologies to find the genetic
variants responsible for rare diseases is a rapidly growing field and has already begun to
transform the way conditions with unknown causes are diagnosed and treated.
Hypothesis: Identification of new genomic variants associated with idiopathic diseases and/or
diseases of unknown etiology will advance medical knowledge about rare and common diseases.
undiagnosed conditions, and to find out how the development of new technologies, such as DNA
sequencing, can increase knowledge of the role genetic variants play in disorders and
possibly how genetic variants may help de-termine the best treatment options.
The recent development of new technologies has increased our ability to understand how
genetic mutations are associated with disease. Using these technologies to find the genetic
variants responsible for rare diseases is a rapidly growing field and has already begun to
transform the way conditions with unknown causes are diagnosed and treated.
Hypothesis: Identification of new genomic variants associated with idiopathic diseases and/or
diseases of unknown etiology will advance medical knowledge about rare and common diseases.
Inclusion Criteria:
1. Individual with rare disorder with previous unknown etiology.
2. Individual with known disorder that does not respond to conventional treatment.
3. Individual experienced a rare adverse event that was a result of the administration of
a pharmacologic or biologic agent, immunization or device.
4. Individual is a family member of the affected individual. -
Exclusion Criteria:
1. Unwilling or unable to grant informed consent if they do not have a legal guardian who
has authority to sign a consent form on their behalf.
2. Have a significant medical, affective, or psychiatric condition that in the
Investigator's opinion may interfere with subject's study participation.
We found this trial at
1
site
Click here to add this to my saved trials
