The Impact of Early Feeding After Radical Cystectomy for Bladder Cancer
| Status: | Enrolling by invitation |
|---|---|
| Conditions: | Cancer, Cancer, Bladder Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | November 2011 |
| End Date: | July 2015 |
Complications after radical cystectomy for bladder cancer range from 30-40%, many of which
are related to bowel function. Patients usually wait to eat until return of bowel function,
although there is evidence that after primary intestinal or colonic surgery, patients may
take food ad lib immediately, and that this is is associated with lower complication rate
and shorter length of stay. The investigators hypothesize that early access to oral enteral
nutrition (food at will) after cystectomy and urinary diversion will reduce the complication
rate both in-hospital and within 90 days after hospital discharge.
are related to bowel function. Patients usually wait to eat until return of bowel function,
although there is evidence that after primary intestinal or colonic surgery, patients may
take food ad lib immediately, and that this is is associated with lower complication rate
and shorter length of stay. The investigators hypothesize that early access to oral enteral
nutrition (food at will) after cystectomy and urinary diversion will reduce the complication
rate both in-hospital and within 90 days after hospital discharge.
Subjects preparing to undergo radical cystectomy and urinary diversion for bladder cancer
that provide informed consent will be randomized into 1 of 2 study arms. The experimental
arm will be offered clear liquid diet 24 hours after extubation and advanced to regular diet
24 hours later if clear liquids are well tolerated. The standard/control arm will receive a
clear liquid diet at the time of return of bowel function, determined by significant flatus
or bowel movements.
Information related to time to return of bowel function, frequency of nausea/vomiting,
hospital complications and length of stay will be recorded. Patients will be followed with
phone calls and chart reviews at 30, 60 and 90 days following surgery. Additional hospital
admissions and/or complications will be determined with those phone calls.
that provide informed consent will be randomized into 1 of 2 study arms. The experimental
arm will be offered clear liquid diet 24 hours after extubation and advanced to regular diet
24 hours later if clear liquids are well tolerated. The standard/control arm will receive a
clear liquid diet at the time of return of bowel function, determined by significant flatus
or bowel movements.
Information related to time to return of bowel function, frequency of nausea/vomiting,
hospital complications and length of stay will be recorded. Patients will be followed with
phone calls and chart reviews at 30, 60 and 90 days following surgery. Additional hospital
admissions and/or complications will be determined with those phone calls.
Inclusion Criteria:
- age >=18
- bladder cancer
- elect radical cystectomy and urinary diversion as treatment
- able to provide informed consent
Exclusion Criteria:
- radical cystectomy for reason other than bladder cancer
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