Alisporivir With pegIFN/RBV in Protease Inhibitor (PI) Treatment Failure Patients With Chronic Hepatitis C
Status: | Terminated |
---|---|
Conditions: | Hepatitis, Hepatitis, Hepatitis |
Therapuetic Areas: | Immunology / Infectious Diseases |
Healthy: | No |
Age Range: | 18 - 70 |
Updated: | 4/21/2016 |
Start Date: | February 2012 |
End Date: | February 2014 |
A Multicenter, Single-arm Trial Evaluating the Safety and Efficacy of DEB025/Alisporivir in Combination With Pegylated Interferon-α2a and Ribavirin (Peg-IFNα2a/RBV) in Protease Inhibitor Treatment Failure Patients With Chronic Hepatitis C Genotype 1
The purpose of this study is to evaluate the overall efficacy, and safety profile, of triple
combination therapy of DEB025/pegIFN/RBV in chronic hepatitis C patients who failed prior
treatment with PI.
combination therapy of DEB025/pegIFN/RBV in chronic hepatitis C patients who failed prior
treatment with PI.
Inclusion criteria:
1. HCV GT1 patients with previous PI treatment failure.
2. Timing of the PI treatment. the minimum time from the last dose of previous PI
treatment to the first dose of study medication is three months.
3. Diagnosed Chronic hepatitis C virus infection
4. Infection with HCV genotype 1
Exclusion criteria:
1. Use of other investigational drugs at the time of enrollment,
2. History of hypersensitivity to any pegIFN or RBV.
3. Any null non-responders to prior pegIFN/RBV treatment,
Other protocol-defined inclusion/exclusion criteria may apply.
We found this trial at
23
sites
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Novartis Novartis, which was created in 1996 by the merger of the Swiss companies Ciba-Geigy...
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