Bupropion SR Plus Counseling for Smoking Cessation
| Status: | Completed |
|---|---|
| Conditions: | Smoking Cessation, Smoking Cessation |
| Therapuetic Areas: | Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | January 2001 |
| End Date: | October 2003 |
A Randomized Controlled Clinical Trial of Bupropion SR and Individual Smoking Cessation Counseling
The purpose of this study was to determine if bupropion plus counseling was more effective
than bupropion alone or counseling alone in helping smokers quit smoking.
than bupropion alone or counseling alone in helping smokers quit smoking.
Inclusion Criteria:
- Smoke 10 or more cigarettes per day
- Expired carbon monoxide (CO) level greater than 9 parts per million (ppm)
- Motivated to quit smoking (score of 3 on 4-point self-report scale)
- Willing to fulfill study requirements
Exclusion Criteria:
- Carbon monoxide breath test score below 9 ppm
- Serious psychopathology (bipolar disorder, psychosis)
- Center for Epidemiologic Studies Depression Scale CES-D)score over 16
- Contraindications for use of bupropion
- History of seizure disorder
- History of eating disorder
- Current heavy drinking
- Risk of pregnancy
- Current breastfeeding
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