Pathogenesis of Hematologic Malignancies
| Status: | Enrolling by invitation |
|---|---|
| Conditions: | Other Indications, Blood Cancer, Blood Cancer, Lymphoma, Hematology, Hematology |
| Therapuetic Areas: | Hematology, Oncology, Other |
| Healthy: | No |
| Age Range: | 1 - Any |
| Updated: | 6/20/2018 |
| Start Date: | September 2008 |
| End Date: | October 2020 |
Pathogenesis of Acute Leukemia, Lymphoproliferative Disorders, and Myeloproliferative Disorders
The cause of blood and bone marrow cancers is poorly understood; however, most research
focuses on how cancer cells grow and develop. Because the causes of these cancers are
unknown, current treatments may be unnecessarily harsh and often do not provide a cure.
Identifying the causes of blood cancers would allow for the development of treatments that
are more likely to provide a cure. To find the causes of blood and bone marrow cancers, we
will look for specific cancer cell abnormalities that are responsible for cancer cell growth.
We will then look to see if drugs that can reverse these abnormalities can kill cancer cells.
focuses on how cancer cells grow and develop. Because the causes of these cancers are
unknown, current treatments may be unnecessarily harsh and often do not provide a cure.
Identifying the causes of blood cancers would allow for the development of treatments that
are more likely to provide a cure. To find the causes of blood and bone marrow cancers, we
will look for specific cancer cell abnormalities that are responsible for cancer cell growth.
We will then look to see if drugs that can reverse these abnormalities can kill cancer cells.
Inclusion Criteria:
- Suspected or confirmed diagnosis of AL, LPD, MDS, or MPD
- Male or female of all ages
- Willing and able to sign informed consent
- Willing guardian consent for participants under 18 years of age
Exclusion Criteria:
- No suspected or confirmed diagnosis of acute leukemias (AL), lymphoproliferative
disorders (LPD), myelodysplastic syndromes (MDS), or myeloproliferative diseases (MPD)
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