Should Chronic Stimulant Medications be Continued Preoperatively in Patients With Attention Deficit Hyperactivity Disorder(ADHD)
| Status: | Completed |
|---|---|
| Conditions: | Neurology, Psychiatric |
| Therapuetic Areas: | Neurology, Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 2 - 18 |
| Updated: | 9/28/2017 |
| Start Date: | November 2012 |
| End Date: | December 2015 |
Patients on chronic stimulant therapy for the treatment of Attention deficit hyperactivity
disorder (ADHD) who are undergoing an outpatient surgical or diagnostic procedure will be
randomized to one of two groups: stimulant medication administered on the day of surgery or
stimulant medication withheld on the day of surgery. The choice of anesthetic pharmacology
will be at the discretion of the attending anesthesiologist, but the endpoint will be a
bispectral index (BIS) between 40 and 60 to ensure adequate and similar depth of anesthesia.
Blood pressure, heart rate and use of vasopressors or anticholinergics will be recorded and
the incidence of hypotension, bradycardia, or administration of medications will be compared
between the two groups.
disorder (ADHD) who are undergoing an outpatient surgical or diagnostic procedure will be
randomized to one of two groups: stimulant medication administered on the day of surgery or
stimulant medication withheld on the day of surgery. The choice of anesthetic pharmacology
will be at the discretion of the attending anesthesiologist, but the endpoint will be a
bispectral index (BIS) between 40 and 60 to ensure adequate and similar depth of anesthesia.
Blood pressure, heart rate and use of vasopressors or anticholinergics will be recorded and
the incidence of hypotension, bradycardia, or administration of medications will be compared
between the two groups.
Inclusion Criteria:
- Patients will be enrolled if they have been diagnosed with ADHD and have been taking
amphetamines and/or methylphenidate for at least the last six months and are
undergoing an outpatient surgical or diagnostic procedure.
Exclusion Criteria:
- Patients will be excluded if they are taking antidepressant medications, anxiolytic
medication, analgesia medications other than acetaminophen or NSAIDs, if they have an
allergy to midazolam, or a have cardiac disease.
- Procedures that entail the likelihood of blood transfusion will be excluded.
We found this trial at
1
site
Nationwide Children's Hospital At Nationwide Children’s, we are creating the future of pediatric health care....
Click here to add this to my saved trials
