Advance Cardiac Resynchronization Therapy (CRT) Registry

Patients who are implanted CRT devices will be enrolled in the study. Once implanted, all
patients will be followed at every 3 months for the first 12 months from the implant. The
responder/non-responder evaluation will occur at 6 months from the implant date. The criteria
used for determining the response to CRT will be captured.

During the office follow-up visits, arrhythmic episode diagnoses, device data and stored
electrogram will be collected. All clinical events such as hospitalization for HF, all-cause
hospitalizations, and all-cause death will also be collected. For patients who are
non-responders to CRT, any re-optimization of the device, i.e., AV/VV interval optimization,
LV lead repositioning and pacing vector reconfiguration as well as modified/new clinical
therapies administered in an attempt to improve HF condition will be collected.

Inclusion Criteria:

- Patient willing and able to sign informed consent

- Patients implanted with any market-approved St. Jude Medical CRT-D/P device with no
prior LV lead placement

Exclusion Criteria:

- Are likely to undergo heart transplantation within the next 12 months

- Are less than 18 years of age

- Are pregnant or planning to become pregnant during the duration of the study

- Are currently participating in a clinical investigation that includes an active
treatment arm

- Have a life expectancy of less than 6 months