Prevention of Ovarian Cancer in Women Participating in Mammography



Status:Completed
Conditions:Ovarian Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:35 - Any
Updated:4/21/2016
Start Date:July 2008
End Date:December 2015

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The primary purpose of this study is to evaluate the effect of systematic identification and
genetic counseling referral on rates of bilateral salpingo-oophorectomy (surgery to remove
both fallopian tubes and ovaries) in women having mammograms at Swedish Medical Center in
Seattle, WA.


Inclusion Criteria:

- Prior mammogram at Swedish Medical Center

- Willing and able to provide informed consent, primary physician information, and
complete study questionnaires

- Must meet at least ONE of the following criteria:

- personal history of breast cancer diagnosed before age 50

- personal history of bilateral breast cancer at any age

- 1 or more first degree relatives with breast cancer diagnosed before age 50

- 3 or more first or second degree relatives with breast cancer at any age

- 2 second degree relatives with breast cancer diagnosed before age 50

- A male relative with breast cancer at any age

- Ashkenazi Jewish with any family history of breast or ovarian cancer

- 1 first or second degree relative with ovarian cancer AND 1 first or second degree
relative with breast cancer at any age

- 2 first degree relatives with ovarian cancer or 2 second degree relatives with
ovarian cancer or 1 first and 1 second degree relative with ovarian cancer.

- A first degree relative with both breast and ovarian cancer (2 primaries in the same
person)

- Personal history of positive genetic test result for any of the following genes:
BRCA1, BRCA2, HNPCC, or P53

- Family history of a positive genetic test result for any of the following genes:
BRCA1, BRCA2 or HNPCC

Exclusion Criteria:

- Previous diagnosis of ovarian cancer

- Prior bilateral-salpingo oophorectomy

- Had a negative genetic test result for a known family genetic mutation
We found this trial at
1
site
1100 Fairview Avenue North
Seattle, Washington 98109
(206) 667-5000
Fred Hutchinson Cancer Research Center At Fred Hutchinson Cancer Research Center, our interdisciplinary teams of...
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mi
from
Seattle, WA
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