Ovarian Tissue Cryopreservation in Females Undergoing Procedures That Will Potentially Lead To Loss of Ovarian Function

The aim of this preliminary study is to retrieve and properly cryopreserve ovarian tissue
for autotransplantation in any premenopausal female whose ovarian function is threatened in
a physiological, pathological or iatrogenic manner in an effort to observe the return of
ovarian endocrine function and development of egg(s) appropriate for use in in vitro
fertilization.

Inclusion Criteria:

- Patient must be female.

- Patient must have a disease process where the disease or its treatment adversely
affects ovarian function.

- Patient must be recommended for this study by their oncologist or specialist.

- Patient (or legally authorized representative) must sign an informed consent.

Exclusion Criteria:

- Patients cannot be male.

- Patients must not be HIV positive.

- Patient cannot have a poor diagnosis such that she is not expected to survive to
adulthood.

- Patient cannot have any medical condition that would contraindicate surgery.

- Patient cannot have any medical condition that would contraindicate general
anesthesia.

- Patient cannot have any medical condition that would contraindicate pregnancy.