Probiotics to Promote Intestinal Health



Status:Completed
Conditions:Infectious Disease
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:18 - Any
Updated:1/27/2019
Start Date:January 2014
End Date:December 2018

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Randomized Controlled Trial of Lactobacillus Rhamnosus GG to Promote Intestinal Health

The purpose of this study is to evaluate the effectiveness of bacteria called Lactobacillus
GG, a Probiotic, in preventing the growth of resistant bacteria in the digestive tract in
patients on broad spectrum antimicrobials.


Inclusion Criteria:

- Adults ≥ 18 years old

- Admission to the non-ICU medical and surgical wards

- On broad spectrum antimicrobials with an anticipated length of stay of >48 hours

Exclusion Criteria:

- Pregnancy

- Non English speaking

- Expected to die within 7 days

- Unable or unwilling to consent

- HIV infection with a CD4 count <200

- Neutropenia with an absolute neutrophil count less than 500 cells/ml (or expected to
drop to less than 500)

- Clinically significant diarrhea or history of C. difficile infection in the last 3
months

- History of VRE colonization and/or infection in the last year

- Transplant recipients
We found this trial at
1
site
660 S Euclid Ave
Saint Louis, Missouri 63110
(314) 362-5000
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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mi
from
Saint Louis, MO
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