Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
| Status: | Completed |
|---|---|
| Conditions: | Pneumonia, Renal Impairment / Chronic Kidney Disease, Cardiology, Hospital, Pulmonary |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Nephrology / Urology, Pulmonary / Respiratory Diseases, Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | September 2013 |
| End Date: | March 2014 |
Intraoperative intravenous fluid management practice varies greatly between
anesthesiologists. Postoperative fluid based weight gain is associated with major morbidity.
Postoperative respiratory complications are associated with increased morbidity, mortality
and hospital costs. The literature shows conflicting data regarding intraoperative fluid
resuscitation volume. No large-scale studies have focused on intraoperative fluid management
and postoperative respiratory dysfunction.
Hypotheses:
Primary - Liberal intraoperative fluid resuscitation is associated with an increased risk of
30 day mortality Secondary - Liberal intraoperative fluid resuscitation is associated with
increased likelihood of postoperative respiratory failure, pulmonary edema, reintubation,
atelectasis, acute kidney injury and peri-extubation oxygen desaturation.
anesthesiologists. Postoperative fluid based weight gain is associated with major morbidity.
Postoperative respiratory complications are associated with increased morbidity, mortality
and hospital costs. The literature shows conflicting data regarding intraoperative fluid
resuscitation volume. No large-scale studies have focused on intraoperative fluid management
and postoperative respiratory dysfunction.
Hypotheses:
Primary - Liberal intraoperative fluid resuscitation is associated with an increased risk of
30 day mortality Secondary - Liberal intraoperative fluid resuscitation is associated with
increased likelihood of postoperative respiratory failure, pulmonary edema, reintubation,
atelectasis, acute kidney injury and peri-extubation oxygen desaturation.
Inclusion Criteria:
- Ages 18 upwards
- Tracheally intubated at the beginning of the procedure and extubated at the end of
the procedure
Exclusion Criteria:
- Cases where the subject had additional surgeries within the previous four weeks
- Ages under 18
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