Single-dose Pharmacokinetics of BMS-626529, Administered as BMS-663068, in Subjects With Hepatic Impairment Compared to Healthy Subjects

Inclusion Criteria:

- Males and females, ages 18 to 70 years, inclusive

- BMI: 18.5 to 38 kg/m2

- Body weight great or equal to 45.5 kg

- Subjects with hepatic impairment

- Subjects with hepatic impairment must be on a stable dose of medication and/or
treatment regimen

- Healthy subjects to the extent possible matched to the first four subjects with
hepatic impairment with regard to age, body weight, and sex, as determined by no
clinically significant deviation from normal in medical history, physical
examination, ECGs, and clinical laboratory determinations

Exclusion Criteria:

- Any major surgery within 4 weeks of study drug administration

- Donation of blood to a blood bank or in a clinical study (except a screening visit)
within 4 weeks of study drug administration (within 2 weeks for plasma only)

- Subject has required additional medication for hepatic encephalopathy within 12
months (6 months for severe hepatic impairment) prior to dosing

- Presence of severe ascites or edema in subjects, as judged by the PI