The Effect of Intranasal Oxytocin on Pain Sensitivity and Threshold
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Healthy Studies |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 20 - 35 |
| Updated: | 10/14/2017 |
| Start Date: | April 2015 |
| End Date: | November 2016 |
The Effect of Intranasal Oxytocin on Pain Sensitivity and Threshold: A Randomized, Double Blinded, Crossover Volunteer Study
Oxytocin is neurohypophysial peptide that acts mainly as a neuromodulator in the brain.The
vast majority of basic science studies suggested a large effect of oxytocin in minimizing
acute pain.Few studies have demonstrated an association between plasma levels of oxytocin and
pain in humans. Since addictive properties of oxytocin have not been described, the drug may
have important application in the management of acute and chronic pain. No studies have
examined the effect of intranasal oxytocin on pain sensitivity and threshold.
vast majority of basic science studies suggested a large effect of oxytocin in minimizing
acute pain.Few studies have demonstrated an association between plasma levels of oxytocin and
pain in humans. Since addictive properties of oxytocin have not been described, the drug may
have important application in the management of acute and chronic pain. No studies have
examined the effect of intranasal oxytocin on pain sensitivity and threshold.
Inclusion Criteria:
- Healthy males and females volunteers, English speaking
Exclusion Criteria:
- Pregnancy, lactation, allergy to preservatives, mental disease, any chronic pain and
any current use of analgesics, anxiety or depression.
We found this trial at
1
site
303 E Chicago Ave
Chicago, Illinois 60611
Chicago, Illinois 60611
(312) 503-8194
Northwestern University Feinberg School of Medicine Northwestern University Feinberg School of Medicine, founded in 1859,...
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