Pituitary Function and Spontaneous Intracranial Hypotension

Previous research has identified spontaneous cerebral spinal fluid leakage as a cause for
spontaneous intracranial hypotension, leading to positional headache patterns. Typical
magnetic resonance imaging findings include subdural fluid collections, enhancement of
pachymenginges, engorgement of venous structures, pituitary hyperemia, and sagging of the
brain (SEEPS). Because pituitary hyperemia has been documented in cases of spontaneous
cerebral spinal fluid leakage and is known to mimic a pituitary tumor or hyperplasia, the
investigators would like to like to assess the clinical manifestations and neuroimaging
abnormalities of SIH patients with regard to the pituitary gland. Specifically, the
investigators are looking to analyze the compression of the pituitary stalk and conduct a
systemic evaluation of pituitary function in SIH patients.