Clinical Study to Validate the Use of a New Point of Care Troponin I Test

This trial is designed as a prospective, multi-center, observational study of "all-comers"
eligible adult subjects presenting to participating Emergency Departments (EDs) with
symptoms suggestive of ACS and/or myocardial ischemia. Subjects presenting with symptoms
suggestive of ACS will be screened and approached for consent for study enrollment by
trained personnel.

After obtaining written informed consent, subjects will have up to 4 blood samples collected
for cTnI testing using the Meritas Troponin I test and Meritas point-of-care (POC) Analyzer.
Blood draws and testing will occur at 4 intervals over 24 hours.

Inclusion Criteria:

1. The informed consent must be signed by the subject, or the subject's legal authorized
representative.

2. 21 years of age or greater at the time of enrollment

3. Subjects presenting to the ED with any symptoms suggestive of ACS and/or myocardial
ischemia, such as but not limited to: subjects currently having chest pain, pressure
or a burning sensation across the precordium and epigastrium, pain that radiates to
neck, shoulder, jaw, back, upper abdomen and either arm.

Exclusion Criteria:

1. Informed consent form not signed

2. Age <21 years

3. Known pregnancy -