180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for Glaucoma



Status:Enrolling by invitation
Conditions:High Blood Pressure (Hypertension), Ocular
Therapuetic Areas:Cardiology / Vascular Diseases, Ophthalmology
Healthy:No
Age Range:18 - Any
Updated:1/27/2017
Start Date:September 2014
End Date:December 2017

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Trial Summary
Trial Overview
Inclusion Criteria

A Randomized Trial of 180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for Glaucoma

Selective laser trabeculoplasty (SLT) is a well-recognized way to lower eye pressure in
treatment of glaucoma. This treatment is performed for 180 degrees or 360 degrees, and
studies at academic centers have shown mixed results when comparing the success rates of 180
degrees or 360 degrees. Both protocols are now typically done by comprehensive
ophthalmologists. However, there is no data that compares success rates of 180 degrees and
360 degrees in the community setting.

This study is designed as a prospective evaluation of the two treatment algorithms for SLT
by measuring intraocular pressure (IOP) after treatment. The hypothesis is that 360 degrees
of SLT will produce a greater reduction in IOP than 180 degrees of SLT at 3 months follow
up.

Inclusion Criteria:

- patients who have been diagnosed with open-angle glaucoma including ocular
hypertension, pseudoexfoliation and pigment dispersion syndrome

- greater than 18 years of age

- initial intraocular pressure (IOP) of ≥ 21 mmHg

Exclusion Criteria:

- prior medical or laser therapy to lower IOP

- previous incisional glaucoma surgery before the study period
We found this trial at
2
sites
Brandywine Eye Center
Wilmington, Delaware 19810
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Wilmington, DE
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Levin Luminais Chronister Eye Associates
Thorndale, Pennsylvania 19372
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from
Thorndale, PA
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