Anesthetic Techniques in EP Patients
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Peripheral Vascular Disease, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 6/14/2018 |
| Start Date: | May 2012 |
| End Date: | December 2018 |
Anesthetic Techniques and the Effect on Cardiac Electrophysiology Procedures
The purpose of this study is to compare different combinations of anesthetic drugs (cause
loss of sensation) in terms of effectiveness, adverse effects, pain relief, and patient
comfort for cardiac electrophysiology procedures. In addition, the investigators are studying
the different anesthetic combinations to determine the best approach in terms of
identification and treatment of arrhythmias.
loss of sensation) in terms of effectiveness, adverse effects, pain relief, and patient
comfort for cardiac electrophysiology procedures. In addition, the investigators are studying
the different anesthetic combinations to determine the best approach in terms of
identification and treatment of arrhythmias.
Anesthetic management in patients coming for electrophysiology procedures is extremely
important and hemodynamically challenging in order to minimize interference on the
electrophysiology studies (EPS) and the ability to trigger arrhythmias while also maintaining
patient comfort and limited movement. Various anesthetic combinations are administered to
provide sedation, analgesia/sedation, or general anesthesia. The ideal agent should produce
rapid loss of consciousness while ensuring cardiovascular stability and prompt recovery with
few adverse effects. Our goal is to study anesthetic techniques and the effect on
electrophysiology procedures to determine the best anesthetic combination in terms of
effectiveness, adverse effects, pain relief, and patient comfort.
Adult patients scheduled for electrophysiology procedures will be enrolled in the study and
randomly assigned to an anesthetic group based on their schedule procedure. Sedation cases
for supraventricular tachycardia (SVT), right ventricular outflow tract (RVOT)/premature
ventricular contraction (PVC) ablation, and atrial flutter (aflutter) procedures will be
randomly assigned to one of three groups: 1) monitored anesthesia (local anesthesia with
sedation and analgesia/pain reliever) with propofol (induce sleep), 2) monitored anesthesia
with ketamine (sedation) + propofol (induce sleep), or 3) monitored anesthesia with
remifentanil infusion (pain reliever) + propofol (induce sleep). Sedation cases for
ventricular tachycardia (VT) ablation and atrial fibrillation (afib) procedures will be
randomly assigned to one of two groups: 1) monitored anesthesia (local anesthesia with
sedation and analgesia/pain reliever) with propofol (induce sleep), or 2) monitored
anesthesia with ketamine (sedation) + propofol (induce sleep). General anesthesia (GA) cases,
including VT ablation and afib procedures will receive general anesthesia (state of
unconsciousness) with sevoflurane (loss of consciousness) + O2. Anesthesia factors, such as
hemodynamics and cerebral oxygen saturation will be continuously monitored and recorded
throughout the study. In addition, we will be looking at standard echocardiogram and
electrophysiology (EP) parameters. The patient's pain level, level of sedation, and
satisfaction will also be measured using scales, assessments, and surveys.
important and hemodynamically challenging in order to minimize interference on the
electrophysiology studies (EPS) and the ability to trigger arrhythmias while also maintaining
patient comfort and limited movement. Various anesthetic combinations are administered to
provide sedation, analgesia/sedation, or general anesthesia. The ideal agent should produce
rapid loss of consciousness while ensuring cardiovascular stability and prompt recovery with
few adverse effects. Our goal is to study anesthetic techniques and the effect on
electrophysiology procedures to determine the best anesthetic combination in terms of
effectiveness, adverse effects, pain relief, and patient comfort.
Adult patients scheduled for electrophysiology procedures will be enrolled in the study and
randomly assigned to an anesthetic group based on their schedule procedure. Sedation cases
for supraventricular tachycardia (SVT), right ventricular outflow tract (RVOT)/premature
ventricular contraction (PVC) ablation, and atrial flutter (aflutter) procedures will be
randomly assigned to one of three groups: 1) monitored anesthesia (local anesthesia with
sedation and analgesia/pain reliever) with propofol (induce sleep), 2) monitored anesthesia
with ketamine (sedation) + propofol (induce sleep), or 3) monitored anesthesia with
remifentanil infusion (pain reliever) + propofol (induce sleep). Sedation cases for
ventricular tachycardia (VT) ablation and atrial fibrillation (afib) procedures will be
randomly assigned to one of two groups: 1) monitored anesthesia (local anesthesia with
sedation and analgesia/pain reliever) with propofol (induce sleep), or 2) monitored
anesthesia with ketamine (sedation) + propofol (induce sleep). General anesthesia (GA) cases,
including VT ablation and afib procedures will receive general anesthesia (state of
unconsciousness) with sevoflurane (loss of consciousness) + O2. Anesthesia factors, such as
hemodynamics and cerebral oxygen saturation will be continuously monitored and recorded
throughout the study. In addition, we will be looking at standard echocardiogram and
electrophysiology (EP) parameters. The patient's pain level, level of sedation, and
satisfaction will also be measured using scales, assessments, and surveys.
Inclusion Criteria:
- Patients scheduled for cardiac electrophysiology procedures
- Patients ≥18 years of age
Exclusion Criteria:
- Gastroesophageal reflux disease (GERD),
- pulmonary hypertension,
- severe pulmonary disease,
- obstructive sleep apnea (OSA) with continuous positive airway pressure therapy (CPAP)
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