Inpatient Self Monitoring and Administration Study (ISMAS)

Inclusion criteria:

1. Male or female, age < 80

2. Most recent hemoglobin A1C within the past 6 months < 12%

3. Recent history of regular self-administered peripheral blood glucose checks as an
outpatient

4. Recent history of insulin self-administration at least twice a day as an outpatient

5. Admitted for a hospitalization anticipated to last at least 3 days

6. Mini Mental Status Examination (MMSE) ≥ 25 at admission and the same or better
post-operatively

7. All patients will be actively followed by the Endocrinology inpatient consultation
team during the hospitalization.

Exclusion criteria:

1. Currently receiving peritoneal or hemodialysis

2. Patients with unstable angina

3. History of myocardial infarction within 3 weeks prior to enrollment

4. Current admission due to or associated with altered mental status or encephalopathy

5. History of an episode of altered mental status or encephalopathy within the 4 weeks
prior to enrollment

6. A confirmed diagnosis of dementia

7. Inability to self-adjust insulin

8. No recent history of ability to perform regular peripheral blood glucose checks

9. Frequency of hypoglycemia (< 60 mg/dL) > twice/week by history

10. Inability to eat without assistance

11. Study objectives will not be pursued in patients during stays in any intensive care
unit.