An Investigational Immuno-therapy Study of Nivolumab, Pomalidomide and Dexamethasone Combinations in Patients With Multiple Myeloma



Status:Active, not recruiting
Conditions:Blood Cancer, Hematology, Hematology
Therapuetic Areas:Hematology, Oncology
Healthy:No
Age Range:18 - Any
Updated:12/15/2018
Start Date:April 21, 2016
End Date:December 8, 2022

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Trial Summary
Trial Overview
Inclusion Criteria

An Open-Label, Randomized Phase 3 Trial of Combinations of Nivolumab, Pomalidomide and Dexamethasone in Relapsed and Refractory Multiple Myeloma

The purpose of this study is to evaluate the safety and effectiveness of several combination
therapies for Multiple Myeloma. Upon entry into the study, patients will be randomized
(assigned by chance) to receive either:

Group 1: nivolumab, pomalidomide and dexamethasone OR Group 2: pomalidomide and dexamethasone
OR Group 3: nivolumab, elotuzumab, pomalidomide and dexamethasone.

Enrollment is closed for all groups.


For more information regarding Bristol-Myers Squibb Clinical Trial participation, please
visit www.BMSStudyConnect.com

Inclusion Criteria:

- Refractory or relapsed and refractory multiple myeloma

- Measurable disease

- Have received ≥ 2 lines of prior therapy which must have included an immune modulatory
drug (IMiD) and a proteasome inhibitor alone or in combination

Exclusion Criteria:

- Solitary bone or extramedullary plasmacytoma disease only

- Active plasma cell leukemia

Other protocol defined inclusion/exclusion criteria could apply
We found this trial at
70
sites
VA Puget Sound Health Care System
1660 South Columbian Way
Seattle, Washington 98108
(206) 762-1010
Phone: 206-277-3101
VA Puget Sound Health Care System With a reputation for excellence, innovation and extraordinary care...
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UAB Comprehensive Cancer Center
1802 6th Avenue South
Birmingham, Alabama 35294
(205) 934-4011
Phone: 205-934-0337
UAB Comprehensive Cancer Center One of the nation’s leading cancer research and treatment centers, the...
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Birmingham, AL
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Roswell Park Cancer Institute
666 Elm Street
Buffalo, New York 14263
(716) 845-2300
Phone: 716-845-4892
Roswell Park Cancer Institute Welcome to Roswell Park Cancer Institute (RPCI), America's first cancer center...
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Memorial Cancer Institute
3700 Johnson Street
Hollywood, Florida 33021
Phone: 954-844-9139
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Hollywood, FL
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Mount Sinai Hospital
1 Gustave L Levy Pl # 271
New York, New York 10029
 (212) 241-6500
Phone: 212-241-8615
Mount Sinai Med Ctr Founded in 1852, The Mount Sinai Hospital is a 1,171-bed, tertiary-care...
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Providence Portland Medical Center
4805 Northeast Glisan Street
Portland, Oregon 97213
(503) 215-1111
Phone: 503-216-3067
Providence Portland Medical Center We strive to give those we serve exceptional, compassionate health care...
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Portland, OR
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University Cancer and Blood Center LLC
Athens, Georgia 30607
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Athens, GA
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Piedmont Cancer Institute, P.C.
Atlanta, Georgia 30318
Phone: 678-298-3242
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Winship Cancer Institute
Atlanta, Georgia 30322
Phone: 404-778-4176
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Augusta University
Augusta, Georgia 30912
Phone: 706-721-0730
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CBCC Global Research
6501 Truxtun Avenue
Bakersfield, California 93309
Phone: 661-616-1688
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St. Agnes Healthcare, Site #185
Baltimore, Maryland 21229
Phone: 667-234-2966
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Regional Cancer Care Associates LLC
Bethesda, Maryland 20817
Phone: 301-571-2016
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University Cancer Institute, LLC
Boynton Beach, Florida 33426
Phone: 561-737-6556
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St. Louis Cancer Care, LLP
Bridgeton, Missouri 63044
Phone: 314-291-3312
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Emily Couric Clinical Cancer Center
Charlottesville, Virginia 22903
Phone: 434-982-3947
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Rush University Medical Center
1653 W. Congress Parkway
Chicago, Illinois 60612
(312) 942-5000
Phone: 312-942-4685
Rush University Medical Center Rush University Medical Center encompasses a 664-bed hospital serving adults and...
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Mid Ohio Oncology Hematology, Inc.
Columbus, Ohio
Phone: 614-383-6236
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Compassionate Cancer Res Grp
Corona, California 92879
Phone: 951-371-2411
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Baylor Research Institute
3310 Live Oak St
Dallas, Texas 75204
(214) 820-2687
Phone: 214-820-6967
Baylor Research Institute Baylor Research Institute (BRI) is a dedicated research center for finding prevention...
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Colorado Blood Cancer Institute
1721 East 19th Ave., Suite #200 & #300
Denver, Colorado 80218
720-754-4800
Phone: 720-754-4414
Colorado Blood Cancer Institute When patients come to the Colorado Blood Cancer Institute, the entire...
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Duke Univ Med Ctr
2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111
Phone: 919-668-6524
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
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Highland Oncology Group
Fayetteville, Arkansas 72703
Phone: 479-685-4168
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Local Institution
Flemington, New Jersey 08822
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Poudre Valley Health Care, Inc.
Fort Collins, Colorado 80528
Phone: 970-297-6150
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Florida Cancer Specialists S.
Fort Myers, Florida 33916
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Ft. Wayne Med Onco-Hema Inc
Fort Wayne, Indiana 46845
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Compassionate Cancer Res Grp
Fountain Valley, California 92708
Phone: 951-276-2760
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West Clinic
Germantown, Tennessee 38138
Phone: 901-683-0055
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Germantown, TN
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St. Mary's Hospital and Medical Center
2635 North 7th Street
Grand Junction, Colorado 81502
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Greenville Health System
Greenville, South Carolina 29615
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John Theurer Cancer Center
Hackensack, New Jersey 07601
Phone: 551-996-5231
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Hattiesburg Clinic
Hattiesburg, Mississippi 39401
Phone: 601-288-2495
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Millennium Oncology
Houston, Texas 77090
Phone: 877-870-2640
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Indiana University Cancer Center
Indianapolis, Indiana 46202
Phone: 317-278-6797
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Cancer Specialists Of North Fl
Jacksonville, Florida 32256
Phone: 904-538-4488
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Broome Oncology, LLC
Johnson City, New York 13790
Phone: 607-763-8065
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Hca Midwest Division
Kansas City, Missouri 64132
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UC San Diego Moores Cancer Center
3855 Health Sciences Dr,
La Jolla, California 92093
(858) 822-6100
Phone: 858-822-5364
UC San Diego Moores Cancer Center Established in 1978, UC San Diego Moores Cancer Center...
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Scripps Health Dba Scripps Clinical Research Services
La Jolla, California 92037
Phone: 858-554-8365
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Lancaster General Hospital
555 N Duke St
Lancaster, Pennsylvania 17602
(717) 544-5511
Phone: 717-544-0511
Lancaster General Hospital For more than a century, Lancaster General Hospital has been a leader...
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Southeast Nebraska Cancer Center
Lincoln, Nebraska 68510
Phone: 402-327-7363
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Elisabethinen Hospital Dept Of Medicine
Linz,
Phone: +4373276764414
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Los Angeles Hematology/Oncology Medical Group
Los Angeles, California 90017
Phone: 213-977-1214
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Ronald Reagan UCLA Medical Center
Los Angeles, California 90095
Phone: 310-206-5756
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Southern Cancer Center
Mobile, Alabama 36608
Phone: 251-607-5283
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Tennessee Oncology, PLLC
250 25th Ave N, Ste 100
Nashville, Tennessee 37023
615-320-5090
Tennessee Oncology, PLLC Since 1976 Tennessee Oncology has been providing quality cancer care. In 2013,...
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Local Institution
New Brunswick, New Jersey 08901
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Yale University School of Medicine
333 Cedar St
New Haven, Connecticut 06504
(203) 432-4771
Phone: 203-737-8358
Yale University School of Medicine Founded in 1810, the Yale School of Medicine is a...
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Weill-Cornell Medical College
New York, New York 10021
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Northern Utah Associates
Ogden, Utah 84403
Phone: 801-387-7166
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University of Oklahoma
1100 N. Lindsay
Oklahoma City, Oklahoma 73104
(405) 271-4000
Phone: 405-271-8777
University of Oklahoma The OU Health Sciences Center is composed of seven health-related colleges located...
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Valley Hospital
Paramus, New Jersey 07450
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Univ of Pennsylvania
3451 Walnut St
Philadelphia, Pennsylvania 19104
1 (215) 898-5000
Univ of Pennsylvania Penn has a long and proud tradition of intellectual rigor and pursuit...
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Torrance Health Association
Redondo Beach, California 90277
Phone: 310-750-3376
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Virginia Cancer Institute
Richmond, Virginia 23235
Phone: 804-287-3000
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Compassionate Cancer Res Grp
Riverside, California 92501
Phone: 951-276-2760
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Washington University
Saint Louis, Missouri 63110
Phone: 314-747-6502
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Saint Louis, MO
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Florida Cancer Specialists
Saint Petersburg, Florida 33705
Phone: 727-216-1143
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Utah Cancer Specialists
Salt Lake City, Utah 84106
Phone: 801-281-6864
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CTRC at UTHSC San Antonio
7979 Wurzbach Road
San Antonio, Texas 78229
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Coastal Integrative Cancer Care
San Luis Obispo, California 93401
Phone: 805-543-5577
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Central Coast Medical Oncology
Santa Maria, California 93454
Phone: 805-346-3461
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Santa Maria, CA
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Donald Guthrie Foundation
Sayre, Pennsylvania 18840
Phone: 570-887-4882
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Sayre, PA
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Mercy Medical Research Institute
Springfield, Missouri 65807
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Florida Cancer Specialists
2626 Care Drive
Tallahassee, Florida 32308
Phone: 850-877-8166
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Scott & White Memorial Hospital
2401 S. 31st Street
Temple, Texas 76508
254-724-2111
Phone: 254-724-5649
Scott & White Memorial Hospital When Arthur C. Scott, MD, and Raleigh R. White Jr.,...
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Florida Cancer Specialists
West Palm Beach, Florida 33401
Phone: 56136641004754
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Wake Forest Baptist Health
Winston-Salem, North Carolina 27157
Phone: 336-716-4542
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Department Of Medicine Division Of Hematology/Oncology
55 North Lake Avenue
Worcester, Massachusetts 01655
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