PORtopulmonary Hypertension Treatment wIth maCitentan ─ a randOmized Clinical Trial
| Status: | Completed |
|---|---|
| Conditions: | High Blood Pressure (Hypertension) |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 1/11/2019 |
| Start Date: | June 23, 2015 |
| End Date: | October 31, 2018 |
A Randomized, Double-blind, Placebo-controlled, Prospective, Multicenter, Parallel Group Study to Assess the Safety and Efficacy of Macitentan in Patients With Portopulmonary Hypertension
24-week study to evaluate the efficacy and safety of macitentan for the treatment of
portopulmonary hypertension.
portopulmonary hypertension.
Main Inclusion Criteria:
- Male or female of at least 18 years of age
- Confirmed diagnosis of portopulmonary hypertension
Main Exclusion Criteria:
- Severe hepatic impairment
- Severe obstructive or restrictive lung disease
- Pulmonary veno-occlusive disease
- Systolic blood pressure (SBP) < 90 mmHg at Screening
- ALT/AST >= 3 x ULN
- Bilirubin >= 3 mg/dL at Screening
- Any known factor or disease that might interfere with treatment compliance, study
conduct, or interpretation of results
We found this trial at
30
sites
Baylor University Medical Center Baylor University Medical Center in Dallas, TX is ranked nationally in...
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Indiana University INDIANA UNIVERSITY is a major multi-campus public research institution, grounded in the liberal...
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University of Miami A private research university with more than 15,000 students from around the...
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Boston University Boston University is no small operation . With over 33,000 undergraduate and graduate...
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University of Cincinnati The University of Cincinnati offers students a balance of educational excellence and...
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Dallas, Texas 75390
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Henry Ford Hospital Founded in 1915 by auto pioneer Henry Ford and now one of...
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10833 Le Conte Ave
Los Angeles, California 90095
Los Angeles, California 90095
(310) 825-4321
David Geffen School of Medicine, UCLA In 2002 Mr. David Geffen announced a $200 million...
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University of Wisconsin-Madison In achievement and prestige, the University of Wisconsin-Madison has long been recognized...
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Univ of Pennsylvania Penn has a long and proud tradition of intellectual rigor and pursuit...
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Porto Alegre, 92020
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