PORtopulmonary Hypertension Treatment wIth maCitentan ─ a randOmized Clinical Trial
| Status: | Completed |
|---|---|
| Conditions: | High Blood Pressure (Hypertension) |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 1/11/2019 |
| Start Date: | June 23, 2015 |
| End Date: | October 31, 2018 |
A Randomized, Double-blind, Placebo-controlled, Prospective, Multicenter, Parallel Group Study to Assess the Safety and Efficacy of Macitentan in Patients With Portopulmonary Hypertension
24-week study to evaluate the efficacy and safety of macitentan for the treatment of
portopulmonary hypertension.
portopulmonary hypertension.
Main Inclusion Criteria:
- Male or female of at least 18 years of age
- Confirmed diagnosis of portopulmonary hypertension
Main Exclusion Criteria:
- Severe hepatic impairment
- Severe obstructive or restrictive lung disease
- Pulmonary veno-occlusive disease
- Systolic blood pressure (SBP) < 90 mmHg at Screening
- ALT/AST >= 3 x ULN
- Bilirubin >= 3 mg/dL at Screening
- Any known factor or disease that might interfere with treatment compliance, study
conduct, or interpretation of results
We found this trial at
30
sites
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Baylor University Medical Center Baylor University Medical Center in Dallas, TX is ranked nationally in...
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Indiana University INDIANA UNIVERSITY is a major multi-campus public research institution, grounded in the liberal...
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University of Miami A private research university with more than 15,000 students from around the...
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Boston University Boston University is no small operation . With over 33,000 undergraduate and graduate...
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University of Cincinnati The University of Cincinnati offers students a balance of educational excellence and...
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Dallas, Texas 75390
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Henry Ford Hospital Founded in 1915 by auto pioneer Henry Ford and now one of...
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10833 Le Conte Ave
Los Angeles, California 90095
Los Angeles, California 90095
(310) 825-4321
David Geffen School of Medicine, UCLA In 2002 Mr. David Geffen announced a $200 million...
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University of Wisconsin-Madison In achievement and prestige, the University of Wisconsin-Madison has long been recognized...
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Univ of Pennsylvania Penn has a long and proud tradition of intellectual rigor and pursuit...
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Porto Alegre, 92020
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